Adenotonsillar hypertrophy : A precipitating factor of cerebrovascular accident in a child with sickle cell anemia

Cerebrovascular accident is one of the most serious complications of sickle cell anemia. The specific factors that predispose patients with sickle cell anemia to stroke are increased disease severity, higher baseline white blood cell count and lower baseline hematocrits. Likewise the presence of a c...

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Bibliographic Details
Published in:Journal of tropical pediatrics (1980) 2000-08, Vol.46 (4), p.246-248
Main Authors: WALI, Y. A, AL-LAMKI, Z, SOLIMAN, H, AL-OKBI, H
Format: Article
Language:English
Subjects:
Adenoids - pathology
Adenoids - surgery
Adolescent
Anemia, Sickle Cell - complications
Anemias. Hemoglobinopathies
Biological and medical sciences
Diseases of red blood cells
Female
Hematologic and hematopoietic diseases
Humans
Hypertrophy - complications
Medical sciences
Palatine Tonsil - pathology
Palatine Tonsil - surgery
Risk Factors
Sleep Apnea Syndromes - etiology
Stroke - etiology
Tropical medicine
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Summary:Cerebrovascular accident is one of the most serious complications of sickle cell anemia. The specific factors that predispose patients with sickle cell anemia to stroke are increased disease severity, higher baseline white blood cell count and lower baseline hematocrits. Likewise the presence of a co-existent alpha thalassemia trait and/or high fetal hemoglobin (HbF%) may reduce the risk. We report a child with sickle cell anemia and marked adenotonsillar hypertrophy resulting in obstructive sleep apnea syndrome. There was no other known risk factor for developing cerebrovascular accident in this child during her hospitalization for adenotonsillectomy.
ISSN:0142-6338
1465-3664
DOI:10.1093/tropej/46.4.246