Diabetes insipidus in neurobrucellosis

Brucellosis is an infection due to Brucella species and is characterized by acute febrile illness, chilly sensations, sweats, weakness, generalized malaise, body aches and headache. The involvement of the nervous system is rare. A few cases have been reported with symptoms and sign of optic neuritis...

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Bibliographic Details
Published in:Clinical neurology and neurosurgery 2000-09, Vol.102 (3), p.163-165
Main Authors: Trifiletti, Rosario R, Restivo, Domenico A, Pavone, Piero, Giuffrida, Salvatore, Parano, Enrico
Format: Article
Language:English
Subjects:
Bacterial diseases
Bacterial diseases of the nervous system. Bacterial myositis
Biological and medical sciences
Brain - microbiology
Brain - pathology
Brucella - isolation & purification
Brucellosis
Brucellosis - complications
Brucellosis - etiology
Brucellosis - microbiology
Central Nervous System Bacterial Infections - etiology
Central Nervous System Bacterial Infections - microbiology
Diabetes insipidus
Diabetes Insipidus - etiology
Human bacterial diseases
Humans
Infectious diseases
Magnetic Resonance Imaging
Male
Medical sciences
Middle Aged
MRI introduction
Neurobrucellosis
Pituitary Diseases - etiology
Pituitary Diseases - microbiology
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Summary:Brucellosis is an infection due to Brucella species and is characterized by acute febrile illness, chilly sensations, sweats, weakness, generalized malaise, body aches and headache. The involvement of the nervous system is rare. A few cases have been reported with symptoms and sign of optic neuritis, meningoencephalitis, meningomyelitis and cranial nerve palsy. We report a case with culture proven neurobrucellosis who presented with diabetes insipidus along with systemic signs. Neuroimaging revealed multiple lesions in brain parenchyma, including the suprasellar region. Both diabetes and suprasellar lesions improved markedly with specific antibiotic therapy.
ISSN:0303-8467
1872-6968
DOI:10.1016/S0303-8467(00)00089-5