Tissue-specific effects of peptides

Synthetic peptides (cytogens) Cortagen, Epithalon, Livagen, and Vilon stimulated the growth of explants from rat brain cortex, subcortical structures, liver, and thymus, respectively, in organotypic cultures. These peptides produced tissue-specific effects: they stimulated the growth of explants fro...

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Bibliographic Details
Published in:Bulletin of experimental biology and medicine 2001-08, Vol.132 (2), p.807-808
Main Author: Khavinson, V K
Format: Article
Language:English
Subjects:
Animals
Cell Division - drug effects
Cerebral Cortex - cytology
Cerebral Cortex - drug effects
Growth Substances - pharmacology
Liver - cytology
Liver - drug effects
Organ Culture Techniques
Organ Specificity
Peptides - pharmacology
Pineal Gland - cytology
Pineal Gland - drug effects
Rats
Rats, Wistar
Thymus Gland - cytology
Thymus Gland - drug effects
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Summary:Synthetic peptides (cytogens) Cortagen, Epithalon, Livagen, and Vilon stimulated the growth of explants from rat brain cortex, subcortical structures, liver, and thymus, respectively, in organotypic cultures. These peptides produced tissue-specific effects: they stimulated the growth of explants from tissues, whose cytomedins (peptide complexes) were used for chemical synthesis.
ISSN:0007-4888
1573-8221
DOI:10.1023/A:1013058701974