Final results of the Cervical Incompetence Prevention Randomized Cerclage Trial (CIPRACT): Therapeutic cerclage with bed rest versus bed rest alone

Objective: To compare preterm delivery rates (before 34 weeks of gestation) and neonatal morbidity and mortality in patients with risk factors or symptoms of cervical incompetence managed with therapeutic McDonald cerclage and bed rest versus bed rest alone. Study Design: Cervical length was measure...

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Bibliographic Details
Published in:American journal of obstetrics and gynecology 2001-11, Vol.185 (5), p.1106-1112
Main Authors: Althuisius, Sietske M., Dekker, Gustaaf A., Hummel, Pieter, Bekedam, Dick J., van Geijn, Herman P.
Format: Article
Language:English
Subjects:
Bed Rest
Biological and medical sciences
Cerclage, Cervical
Cervical incompetence
Cervix Uteri - diagnostic imaging
Cervix Uteri - surgery
Diseases of mother, fetus and pregnancy
Female
Gynecology. Andrology. Obstetrics
Humans
Incidence
Infant, Newborn
Infant, Newborn, Diseases - prevention & control
Medical sciences
Obstetric Labor, Premature - epidemiology
Obstetric Labor, Premature - prevention & control
Pregnancy
Pregnancy. Fetus. Placenta
preterm delivery
randomized trial
Risk Factors
therapeutic cerclage
Tropical medicine
Ultrasonography
Uterine Cervical Incompetence - etiology
Uterine Cervical Incompetence - prevention & control
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Summary:Objective: To compare preterm delivery rates (before 34 weeks of gestation) and neonatal morbidity and mortality in patients with risk factors or symptoms of cervical incompetence managed with therapeutic McDonald cerclage and bed rest versus bed rest alone. Study Design: Cervical length was measured in patients with risk factors or symptoms of cervical incompetence. Risk factors for cervical incompetence included previous preterm delivery before 34 weeks of gestation that met clinical criteria for the diagnosis of cervical incompetence, previous preterm premature rupture of membranes before 32 weeks of gestation, history of cold knife conization, diethylstilbestrol exposure, and uterine anomaly. When a cervical length of
ISSN:0002-9378
1097-6868
DOI:10.1067/mob.2001.118655