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Potassium iodide in dermatology: A 19th century drug for the 21st century—uses, pharmacology, adverse effects, and contraindications
Potassium iodide (KI) is a useful drug in the dermatologic armamentarium. It is successfully used for inflammatory dermatoses, most notably erythema nodosum, subacute nodular migratory panniculitis, nodular vasculitis, erythema multiforme, and Sweet's syndrome. KI is also successfully used for...
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Published in: | Journal of the American Academy of Dermatology 2000-10, Vol.43 (4), p.691-697 |
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container_title | Journal of the American Academy of Dermatology |
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creator | Sterling, J.Barton Heymann, Warren R. |
description | Potassium iodide (KI) is a useful drug in the dermatologic armamentarium. It is successfully used for inflammatory dermatoses, most notably erythema nodosum, subacute nodular migratory panniculitis, nodular vasculitis, erythema multiforme, and Sweet's syndrome. KI is also successfully used for cutaneous and lymphocutaneous sporotrichosis. The precise mechanism by which KI acts is unknown. Although many minor side effects are common with this drug, major side effects can occur in pregnant patients and those with a history of kidney or thyroid disease. This article reviews the pharmacology, mechanism of action, indications, contraindications, and adverse effects of KI as a therapeutic agent. (J Am Acad Dermatol 2000;43:691-7.) |
doi_str_mv | 10.1067/mjd.2000.107247 |
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It is successfully used for inflammatory dermatoses, most notably erythema nodosum, subacute nodular migratory panniculitis, nodular vasculitis, erythema multiforme, and Sweet's syndrome. KI is also successfully used for cutaneous and lymphocutaneous sporotrichosis. The precise mechanism by which KI acts is unknown. Although many minor side effects are common with this drug, major side effects can occur in pregnant patients and those with a history of kidney or thyroid disease. This article reviews the pharmacology, mechanism of action, indications, contraindications, and adverse effects of KI as a therapeutic agent. 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It is successfully used for inflammatory dermatoses, most notably erythema nodosum, subacute nodular migratory panniculitis, nodular vasculitis, erythema multiforme, and Sweet's syndrome. KI is also successfully used for cutaneous and lymphocutaneous sporotrichosis. The precise mechanism by which KI acts is unknown. Although many minor side effects are common with this drug, major side effects can occur in pregnant patients and those with a history of kidney or thyroid disease. This article reviews the pharmacology, mechanism of action, indications, contraindications, and adverse effects of KI as a therapeutic agent. (J Am Acad Dermatol 2000;43:691-7.)</description><subject>Biological and medical sciences</subject><subject>Humans</subject><subject>Medical sciences</subject><subject>Pharmacology. Drug treatments</subject><subject>Potassium Iodide - pharmacology</subject><subject>Potassium Iodide - therapeutic use</subject><subject>Skin Diseases - drug therapy</subject><subject>Skin, nail, hair, dermoskeleton</subject><subject>Thyroid Gland - drug effects</subject><subject>Thyroid Gland - metabolism</subject><issn>0190-9622</issn><issn>1097-6787</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2000</creationdate><recordtype>article</recordtype><recordid>eNp1kLFuFDEQhi0EIpdATYcsIVFlE9u7sTFdFEFAigQF1NasPc452rUP2xvpulQ8AU_Ik-DjDqioLGu-f_TPR8gLzs44k-p8vnNngrHdT4lBPSIrzrTqpHqjHpMV45p1WgpxRI5LuWucHnr1lBxxztgghV6R759ThVLCMtOQXHBIQ6QO8ww1Tel2-5ZeUq7rmlqMdclb6vJyS33KtK6RCl7qn8nPhx9LwXJKN2tocfs7fkrB3WMuSNF7tLWNITpqU6wZQnTBQg0plmfkiYep4PPDe0K-vn_35epDd_Pp-uPV5U1nW_Hajd4BUxp6Po4MuL-wIyimuBO9BNDtVO4GzdvZfGQavRN64EJzqXtnpeb9CXm937vJ6duCpZo5FIvTBBHTUowSQl80lQ0834M2p1IyerPJYYa8NZyZnXrT1JuderNX3xIvD6uXcUb3jz-4bsCrAwDFwuQzRBvKX05pKeWuod5T2DTcB8ym2IDRogu5CTQuhf9W-AX7MKEA</recordid><startdate>20001001</startdate><enddate>20001001</enddate><creator>Sterling, J.Barton</creator><creator>Heymann, Warren R.</creator><general>Mosby, Inc</general><general>Elsevier</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>20001001</creationdate><title>Potassium iodide in dermatology: A 19th century drug for the 21st century—uses, pharmacology, adverse effects, and contraindications</title><author>Sterling, J.Barton ; Heymann, Warren R.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c437t-bfda079a31bb0a1f5cba7071d236aa99621d4911901b09efd2941291693dc6913</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2000</creationdate><topic>Biological and medical sciences</topic><topic>Humans</topic><topic>Medical sciences</topic><topic>Pharmacology. Drug treatments</topic><topic>Potassium Iodide - pharmacology</topic><topic>Potassium Iodide - therapeutic use</topic><topic>Skin Diseases - drug therapy</topic><topic>Skin, nail, hair, dermoskeleton</topic><topic>Thyroid Gland - drug effects</topic><topic>Thyroid Gland - metabolism</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Sterling, J.Barton</creatorcontrib><creatorcontrib>Heymann, Warren R.</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Journal of the American Academy of Dermatology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Sterling, J.Barton</au><au>Heymann, Warren R.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Potassium iodide in dermatology: A 19th century drug for the 21st century—uses, pharmacology, adverse effects, and contraindications</atitle><jtitle>Journal of the American Academy of Dermatology</jtitle><addtitle>J Am Acad Dermatol</addtitle><date>2000-10-01</date><risdate>2000</risdate><volume>43</volume><issue>4</issue><spage>691</spage><epage>697</epage><pages>691-697</pages><issn>0190-9622</issn><eissn>1097-6787</eissn><coden>JAADDB</coden><abstract>Potassium iodide (KI) is a useful drug in the dermatologic armamentarium. 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subjects | Biological and medical sciences Humans Medical sciences Pharmacology. Drug treatments Potassium Iodide - pharmacology Potassium Iodide - therapeutic use Skin Diseases - drug therapy Skin, nail, hair, dermoskeleton Thyroid Gland - drug effects Thyroid Gland - metabolism |
title | Potassium iodide in dermatology: A 19th century drug for the 21st century—uses, pharmacology, adverse effects, and contraindications |
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