Coronary artery calcium evaluation by electron beam computed tomography and its relation to new cardiovascular events

Electron beam computed tomography is widely used to screen for coronary artery calcium (CAC). We evaluated the relation of CAC to future cardiovascular disease events in 926 asymptomatic persons (735 men and 191 women, mean age 54 years) who underwent a baseline electron beam computed tomographic sc...

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Bibliographic Details
Published in:The American journal of cardiology 2000-09, Vol.86 (5), p.495-498
Main Authors: Wong, Nathan D, Hsu, Jeffrey C, Detrano, Robert C, Diamond, George, Eisenberg, Harvey, Gardin, Julius M
Format: Article
Language:English
Subjects:
Adult
Aged
Aged, 80 and over
Biological and medical sciences
Calcinosis - complications
Calcinosis - diagnostic imaging
Calcium
Cardiovascular disease
Cardiovascular Diseases - epidemiology
Cardiovascular Diseases - etiology
Cardiovascular system
Coronary Disease - complications
Coronary Disease - diagnostic imaging
Female
Humans
Incidence
Investigative techniques, diagnostic techniques (general aspects)
Male
Medical sciences
Middle Aged
Prognosis
Proportional Hazards Models
Radiodiagnosis. Nmr imagery. Nmr spectrometry
Tomography
Tomography, X-Ray Computed - methods
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Summary:Electron beam computed tomography is widely used to screen for coronary artery calcium (CAC). We evaluated the relation of CAC to future cardiovascular disease events in 926 asymptomatic persons (735 men and 191 women, mean age 54 years) who underwent a baseline electron beam computed tomographic scan. All subjects included in this report returned a follow-up questionnaire 2 to 4 years (mean 3.3) after scanning, inquiring about myocardial infarction, stroke, and revascularizations. Sixty percent of men and 40% of women had a positive scan at baseline. Twenty-eight cardiovascular events occurred and were confirmed by blinded medical record review. The presence of CAC (a total calcium score of >0) and increasing score quartiles were related to the occurrence of new myocardial infarction (p
ISSN:0002-9149
1879-1913
DOI:10.1016/S0002-9149(00)01000-6