Turbo ASL: Arterial spin labeling with higher SNR and temporal resolution

A modified pulsed arterial spin labeling (ASL) technique is introduced here that has both higher temporal resolution and higher SNR per unit time than existing ASL techniques. In this technique, the time TI between the application of the tag and image acquisition is longer than the repetition time T...

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Bibliographic Details
Published in:Magnetic resonance in medicine 2000-10, Vol.44 (4), p.511-515
Main Authors: Wong, Eric C., Luh, Wen-Ming, Liu, Thomas T.
Format: Article
Language:English
Subjects:
arterial spin labeling
Arteries
Biological and medical sciences
Brain - anatomy & histology
cerebral blood flow
Humans
Investigative techniques, diagnostic techniques (general aspects)
Magnetic Resonance Imaging - methods
Medical sciences
Nervous system
perfusion
Radiodiagnosis. Nmr imagery. Nmr spectrometry
Spin Labels
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Description
Summary:A modified pulsed arterial spin labeling (ASL) technique is introduced here that has both higher temporal resolution and higher SNR per unit time than existing ASL techniques. In this technique, the time TI between the application of the tag and image acquisition is longer than the repetition time TR, allowing for the use of greatly reduced TR values without a significant decrease in the amplitude of the ASL signal. This improves both the temporal resolution and the sensitivity of ASL for functional brain mapping. Magn Reson Med 44:511–515, 2000. © 2000 Wiley‐Liss, Inc.
ISSN:0740-3194
1522-2594
DOI:10.1002/1522-2594(200010)44:4<511::AID-MRM2>3.0.CO;2-6