Nuclear and cellular volumetric alterations in oral lichen planus and lichenoid lesions : a histomorphometric study

There is presently no line of distinction between oral lichen planus and other oral lichenoid lesions. The aim of this study is to determine using histomorphometry, the differences between these lesions. Paraffin sections from 7 normal buccal epithelium, 19 oral lichen planus (LP), 14 oral lichenoid...

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Bibliographic Details
Published in:Journal of Oral Science 2001, Vol.43(3), pp.151-157
Main Authors: Khoo, Suan-Phaik, Primasari, Ameta, Saub, Roslan
Format: Article
Language:English
Subjects:
Adult
Case-Control Studies
Cell Nucleus - pathology
Cell Size
cellular volumes
Dentistry
Diagnosis, Differential
Epithelial Cells - pathology
Female
Humans
Lichen Planus, Oral - pathology
Lichenoid Eruptions - pathology
Lupus Erythematosus, Discoid - pathology
Male
Middle Aged
Mouth Mucosa - pathology
nuclear
oral lichenoid lesions
Retrospective Studies
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Summary:There is presently no line of distinction between oral lichen planus and other oral lichenoid lesions. The aim of this study is to determine using histomorphometry, the differences between these lesions. Paraffin sections from 7 normal buccal epithelium, 19 oral lichen planus (LP), 14 oral lichenoid lesions (LL) and 7 discoid lupus erythematosus-like lesions (DLE-II) were selected. The nuclear volume (VN) and cellular-volume (VCELL) of the epithelium were assessed using an image analyser. The VN and VCELL derived for both basal and spinal strata in LP and DLE-II were 2.3 times more than that of normal tissues. There was a significant difference between LP and LL (P
ISSN:1343-4934
1880-4926
DOI:10.2334/josnusd.43.151