A comparison of the contractile properties of human myometrium obtained from the upper and lower uterine segments

This study compared the contractile characteristics of myometrium taken from upper and lower uterine segments. Biopsies were obtained from women undergoing classical caesarean section. Myometrial strips were dissected and mounted in an organ bath, and the contractions were recorded. The cross sectio...

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Bibliographic Details
Published in:BJOG : an international journal of obstetrics and gynaecology 2000-10, Vol.107 (10), p.1309-1311
Main Authors: Luckas, Murray J. M., Wray, Susan
Format: Article
Language:English
Subjects:
Female
Humans
Myometrium - physiology
Oxytocics - pharmacology
Oxytocin - pharmacology
Potassium Chloride - pharmacology
Pregnancy
Uterine Contraction - physiology
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Summary:This study compared the contractile characteristics of myometrium taken from upper and lower uterine segments. Biopsies were obtained from women undergoing classical caesarean section. Myometrial strips were dissected and mounted in an organ bath, and the contractions were recorded. The cross sectional area of the contractile elements within the strips was measured enabling strips of differing dimensions to be compared. There were no significant differences in the contractile rate and force production produced by myometrium from the upper and lower segments. This study demonstrated that for contractile studies, the use of lower segment is appropriate. The results fail to demonstrate any functional regionality of the human uterus in terms of contractility.
ISSN:1470-0328
1471-0528
DOI:10.1111/j.1471-0528.2000.tb11626.x