Phytochemical and pharmacological studies on Monechma ciliatum

The leaves of Monechma ciliatum were found to contain alkaloids, glycosides, proteins, tannins and saponins. The hot methanol extract (HME) of the leaves, previously found to have potent oxytocic effect in various species was fractionated in various solvents and the fractions analysed chemically and...

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Bibliographic Details
Published in:Journal of ethnopharmacology 2000-11, Vol.73 (1), p.289-292
Main Authors: Uguru, Mary O, Evans, F
Format: Article
Language:English
Subjects:
Alkaloids
Amino acids
Animals
Bioassay
Biological and medical sciences
Female
General pharmacology
Hot methanol extract
Medical sciences
Monechma ciliatum
Oxytocic principles
Oxytocics - chemistry
Oxytocics - isolation & purification
Oxytocics - pharmacology
Pharmacognosy. Homeopathy. Health food
Pharmacology. Drug treatments
Phytochemical screening
Plant Extracts - chemistry
Plant Extracts - isolation & purification
Plant Extracts - pharmacology
Plant Leaves - chemistry
Rat uterus
Rats
Steroids
Uterus - drug effects
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Summary:The leaves of Monechma ciliatum were found to contain alkaloids, glycosides, proteins, tannins and saponins. The hot methanol extract (HME) of the leaves, previously found to have potent oxytocic effect in various species was fractionated in various solvents and the fractions analysed chemically and also assayed on the rat uterus in an attempt to identify the chemical constituents present and in particular the oxytocic principle. Positive reaction with ninhydrin spray suggests that the oxytocic constituent is an amino acidic derivative.
ISSN:0378-8741
1872-7573
DOI:10.1016/S0378-8741(00)00236-1