Striated palmoplantar keratoderma of Brunauer-Fohs-Siemens

A 67‐year‐old African American man presented with callosities of his hands (which he had since adolescence) that were exacerbated by manual labor. His father suffered severe callosities of his feet, but no other family member was afflicted. Physical examination revealed symmetrically distributed lin...

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Bibliographic Details
Published in:International journal of dermatology 2001-10, Vol.40 (10), p.644-645
Main Authors: Kotcher, Lauren B., Jih, Ming H., White, Katherine L., Kimyai-Asadi, Arash
Format: Article
Language:English
Subjects:
Aged
Biological and medical sciences
Dermatology
Dyskeratosis
Hand
Humans
Keratoderma, Palmoplantar - pathology
Male
Medical sciences
Skin - pathology
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Summary:A 67‐year‐old African American man presented with callosities of his hands (which he had since adolescence) that were exacerbated by manual labor. His father suffered severe callosities of his feet, but no other family member was afflicted. Physical examination revealed symmetrically distributed linear hyperkeratotic plaques on the palms extending onto the full length of the volar aspect of his digits (Fig. 1). There was no personal or family history of hair, nail, or dental abnormalities. Histologic evaluation showed marked acanthosis, hypergranulosis, and hyperkeratosis of the lesions (Fig. 2). There was no evidence of epidermolytic hyperkeratosis. 1 Linear hyperkeratotic plaques extending the length of the digits and focally present on the palms 2 Marked acanthosis, hypergranulosis, and hyperkeratosis of palmoplantar skin (hematoxylin and eosin, × 200)
ISSN:0011-9059
1365-4632
DOI:10.1046/j.1365-4362.2001.01288.x