Plasma total homocysteine and subarachnoid haemorrhage in a co-factor replete population

Mild hyperhomocysteinaemia is a postulated risk factor for occlusive vascular disease, including stroke. Subarachnoid haemorrhage (SAH) has an annual incidence of 10-20 per 100,000 and accounts for 5-10% of all strokes. Measurement of plasma total homocysteine (tHcy) in a cohort of vitamin B12 and f...

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Bibliographic Details
Published in:Amino acids 2001-01, Vol.21 (3), p.237-241
Main Authors: McEvoy, A W, Marras, C, Kitchen, N D, Briddon, A
Format: Article
Language:English
Subjects:
Adult
Aged
Aged, 80 and over
Case-Control Studies
Cross-Sectional Studies
Female
Folic acid
Folic Acid - blood
Hemorrhage
Homocysteine
Homocysteine - blood
Humans
Incidence
Male
Middle Aged
Prospective Studies
Risk analysis
Risk factors
Subarachnoid hemorrhage
Subarachnoid Hemorrhage - blood
Subarachnoid Hemorrhage - epidemiology
Vascular diseases
Vitamin B 12 - blood
Vitamin B12
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Summary:Mild hyperhomocysteinaemia is a postulated risk factor for occlusive vascular disease, including stroke. Subarachnoid haemorrhage (SAH) has an annual incidence of 10-20 per 100,000 and accounts for 5-10% of all strokes. Measurement of plasma total homocysteine (tHcy) in a cohort of vitamin B12 and folate replete patients did not reveal any association between tHcy and the aetiology of SAH.
ISSN:0939-4451
1438-2199
DOI:10.1007/s007260170009