The Kings Schizotypy Questionnaire as a quantitative measure of schizophrenia liability

We used a new self-report measure, the Kings Schizotypy Questionnaire (KSQ; Williams, M. The psychometric assessment of schizotypal personality. PhD thesis. Institute of Psychiatry, University of London, 1993), to investigate schizotypy as a quantitative measure of familial liability to schizophreni...

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Bibliographic Details
Published in:Schizophrenia research 2000-10, Vol.45 (3), p.213-221
Main Authors: Jones, L.A., Cardno, A.G., Murphy, K.C., Sanders, R.D., Gray, M.Y., McCarthy, G., McGuffin, P., Owen, M.J., Williams, J.
Format: Article
Language:English
Subjects:
Adult
Aged
Analysis of Variance
Biological and medical sciences
Case-Control Studies
Diagnosis, Differential
Family Health
Female
Genetic Predisposition to Disease
Humans
Ireland - epidemiology
Kings Schizotypy Questionnaire
Male
Medical sciences
Middle Aged
Personality Inventory
Psychology. Psychoanalysis. Psychiatry
Psychometrics. Diagnostic aid systems
Psychopathology. Psychiatry
Schizophrenia - diagnosis
Schizophrenia - epidemiology
Schizophrenia - genetics
Schizophrenia liability
Schizotypal Personality Disorder - diagnosis
Schizotypy
Sensitivity and Specificity
Techniques and methods
United Kingdom - epidemiology
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Summary:We used a new self-report measure, the Kings Schizotypy Questionnaire (KSQ; Williams, M. The psychometric assessment of schizotypal personality. PhD thesis. Institute of Psychiatry, University of London, 1993), to investigate schizotypy as a quantitative measure of familial liability to schizophrenia. The KSQ was administered to 135 DSM-IV schizophrenia probands, 153 of their healthy first-degree relatives, and 267 control subjects. We found that the questionnaire clearly differentiated schizophrenic from non-schizophrenic individuals, but failed to differentiate the relatives from controls. Possible reasons for this include defensive responding among relatives, self-selection bias among relatives, differences in data collection methods, and the possibility that positive aspects of schizotypy may not be closely related to familial liability to schizophrenia.
ISSN:0920-9964
1573-2509
DOI:10.1016/S0920-9964(99)00183-8