CAG repeat length of the androgen receptor gene in Japanese males with cryptorchidism

We have analysed the CAG repeat length in exon 1 of the androgen receptor gene in 48 Japanese males with cryptorchidism and 100 fertile Japanese males. The CAG repeat length was 23.4 ± 0.48 (mean ± SE) (range 16–32, median 23) in cryptorchid patients and 23.5 ± 0.29 (range 15–32, median 23) in norma...

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Bibliographic Details
Published in:Molecular human reproduction 2000-11, Vol.6 (11), p.973-975
Main Authors: Sasagawa, Isoji, Suzuki, Yasuhiro, Tateno, Tadashi, Nakada, Teruhiro, Muroya, Koji, Ogata, Tsutomu
Format: Article
Language:English
Subjects:
Adolescent
Adult
androgen receptor
Asian Continental Ancestry Group - genetics
Base Sequence
Biological and medical sciences
CAG repeat
Case-Control Studies
cryptorchidism
Cryptorchidism - genetics
Fundamental and applied biological sciences. Psychology
Genetics of eukaryotes. Biological and molecular evolution
Gynecology. Andrology. Obstetrics
Human
Humans
Japan
Male
Male genital diseases
Medical sciences
Molecular Sequence Data
Non tumoral diseases
Population genetics, reproduction patterns
Receptors, Androgen - genetics
Trinucleotide Repeats
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Summary:We have analysed the CAG repeat length in exon 1 of the androgen receptor gene in 48 Japanese males with cryptorchidism and 100 fertile Japanese males. The CAG repeat length was 23.4 ± 0.48 (mean ± SE) (range 16–32, median 23) in cryptorchid patients and 23.5 ± 0.29 (range 15–32, median 23) in normal males. There was no significant difference between the two groups. The expansion of the CAG repeats in exon 1 of the androgen receptor gene is unlikely to constitute a major cause of cryptorchidism.
ISSN:1360-9947
1460-2407
1460-2407
DOI:10.1093/molehr/6.11.973