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Effect of degree of blood pressure on the hypercoagulable state in chronic atrial fibrillation

To investigate the hypothesis that higher levels of blood pressure would further promote the hypercoagulable state in atrial fibrillation (AF) by increasing the degree of hemostatic abnormalities, we studied 82 consecutive patients with chronic nonvalvular AF who were not taking antithrombotic thera...

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Published in:	The American journal of cardiology 2000-10, Vol.86 (7), p.795-797
Main Authors:	Li-Saw-Hee, Foo Leong, Blann, Andrew D, Lip, Gregory Y.H
Format:	Article
Language:	English
Subjects:	Aged Atrial Fibrillation - blood Atrial Fibrillation - physiopathology Biological and medical sciences Blood Coagulation - physiology Blood pressure Blood Pressure - physiology Cardiac arrhythmia Cardiac dysrhythmias Cardiology Cardiology. Vascular system Chronic Disease Drug therapy Female Fibrin Fibrinogen Degradation Products - metabolism Fibrinogen - metabolism Heart Humans Male Medical sciences Middle Aged Risk Factors von Willebrand Factor - metabolism
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creator	Li-Saw-Hee, Foo Leong Blann, Andrew D Lip, Gregory Y.H
description	To investigate the hypothesis that higher levels of blood pressure would further promote the hypercoagulable state in atrial fibrillation (AF) by increasing the degree of hemostatic abnormalities, we studied 82 consecutive patients with chronic nonvalvular AF who were not taking antithrombotic therapy. Patients with AF had higher levels of plasma fibrin D-dimer, von Willebrand factor, and fibrinogen than controls in sinus rhythm, and no differences between tertiles of either systolic, diastolic, or mean blood pressure were found, suggesting other mechanisms may be contributing to the hypercoagulable state in AF.
doi_str_mv	10.1016/S0002-9149(00)01086-9
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subjects	Aged Atrial Fibrillation - blood Atrial Fibrillation - physiopathology Biological and medical sciences Blood Coagulation - physiology Blood pressure Blood Pressure - physiology Cardiac arrhythmia Cardiac dysrhythmias Cardiology Cardiology. Vascular system Chronic Disease Drug therapy Female Fibrin Fibrinogen Degradation Products - metabolism Fibrinogen - metabolism Heart Humans Male Medical sciences Middle Aged Risk Factors von Willebrand Factor - metabolism
title	Effect of degree of blood pressure on the hypercoagulable state in chronic atrial fibrillation
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