Intrathyroid parathyroid gland and neonatal primary hyperparathyroidism

Neonatal hyperparathyroidism (NPHP) is exceedingly rare and often fatal. A neonate is presented with a serum calcium concentration of 33 mg/dL, an intrathyroid parathyroid gland, and a family history of hypocalciuric hypercalcemia (FHH). She underwent successful total parathyroidectomy. Six years la...

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Bibliographic Details
Published in:Journal of pediatric surgery 2000-10, Vol.35 (10), p.1517-1519
Main Authors: Janik, James E., Bloch, Clifford A., Janik, Joseph S.
Format: Article
Language:English
Subjects:
Biological and medical sciences
Calcium - blood
Endocrinopathies
Female
Humans
Hyperparathyroidism - blood
Hyperparathyroidism - diagnosis
Hyperparathyroidism - surgery
Infant, Newborn
intrathyroid parathyroid gland
Medical sciences
neonate
Non tumoral diseases. Target tissue resistance. Benign neoplasms
Parathyroid Glands - pathology
Parathyroidectomy
Parathyroids. Parafollicular cells. Cholecalciferol. Phosphocalcic homeostasis (diseases)
Primary hyperparathyroidism
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Summary:Neonatal hyperparathyroidism (NPHP) is exceedingly rare and often fatal. A neonate is presented with a serum calcium concentration of 33 mg/dL, an intrathyroid parathyroid gland, and a family history of hypocalciuric hypercalcemia (FHH). She underwent successful total parathyroidectomy. Six years later, the child is normocalcemic and developmentally normal, requiring calcium and calcitrol replacement. The results of this case support the concept that NPHP is associated with parathyroid hyperplasia and is part of a continuum that includes FHH. J Pediatr Surg 35:1517-1519. Copyright © 2000 by W.B. Saunders Company.
ISSN:0022-3468
1531-5037
DOI:10.1053/jpsu.2000.16430