Two Cases of Confluent and Reticulate Papillomatosis: Successful Treatments of One Case with Cefdinir and Another with Minocycline

The present report presents two cases of confluent and reticulate papillomatosis. Case 1 was a 24‐year‐old man who had suffered from skin eruptions for six months, and Case 2 was a 19‐year‐old woman who had had this disease for three days. In both patients, reticular dark brown papules, accompanied...

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Bibliographic Details
Published in:Journal of dermatology 2000-09, Vol.27 (9), p.598-603
Main Authors: Yamamoto, Asayo, Okubo, Yukari, Oshima, Haruko, Oh‐i, Tsunao, Koga, Michiyuki
Format: Article
Language:English
Subjects:
Adult
Anti-Bacterial Agents - therapeutic use
Anti-Infective Agents - therapeutic use
Arm
Cefdinir
Cephalosporins - therapeutic use
confluent and reticulate papillomatosis
Female
Humans
ketokonazole
Male
minocycline
Minocycline - therapeutic use
Neck
Papilloma - drug therapy
Papilloma - pathology
Skin Neoplasms - drug therapy
Skin Neoplasms - pathology
Thorax
treatment
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Summary:The present report presents two cases of confluent and reticulate papillomatosis. Case 1 was a 24‐year‐old man who had suffered from skin eruptions for six months, and Case 2 was a 19‐year‐old woman who had had this disease for three days. In both patients, reticular dark brown papules, accompanied by mild keratosis and infiltration, spread from the trunk to the neck and upper arm. Direct light microscopy did not detect the presence of any fungi, and histopathological examinations confirmed hyperkeratosis, acanthosis, papillomatosis, and mild small‐round‐cell infiltration. Thus, these patients were diagnosed as confluent and reticulate papillomatosis. Neither one had diabetes or thyroid dysfunction. In Case 1, cefdinir was effective, and in Case 2, minocycline hydrochloride and ketoconazole were effective. To the best of our knowledge, this was the first documented case of confluent and reticulate papillomatosis responding to cefdinir.
ISSN:0385-2407
1346-8138
DOI:10.1111/j.1346-8138.2000.tb02235.x