Molecular genetics in Aspergillus fumigatus

Manipulation of the genome of the human pathogen Aspergillus fumigatus is not well developed. Approaches and data from related model organisms are being used to develop molecular genetic systems in A. fumigatus; for example, the molecular typing of strains during infection. A genome-sequencing progr...

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Bibliographic Details
Published in:Current Opinion in Microbiology 2000-10, Vol.3 (5), p.468-474
Main Authors: Brookman, Jayne L, Denning, David W
Format: Article
Language:English
Subjects:
Aspergillosis - epidemiology
Aspergillus fumigatus
Aspergillus fumigatus - genetics
Aspergillus fumigatus - growth & development
Aspergillus fumigatus - pathogenicity
DNA Transposable Elements
Genome, Fungal
Genomics
Models, Biological
Molecular Biology
Mycological Typing Techniques
Transformation, Genetic
Virulence - genetics
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Summary:Manipulation of the genome of the human pathogen Aspergillus fumigatus is not well developed. Approaches and data from related model organisms are being used to develop molecular genetic systems in A. fumigatus; for example, the molecular typing of strains during infection. A genome-sequencing programme has begun and will form the basis for future development.
ISSN:1369-5274
1879-0364
DOI:10.1016/S1369-5274(00)00124-7