Conjugated linoleic acid: implications for human health

Conjugated linoleic acid (CLA) is being sold as a panacea that has the capability of reducing or eliminating cancer, preventing heart disease, improving immune function, and altering body composition to treat obesity or build lean body mass. Unfortunately, there has been very little published human...

Full description

Saved in:
Bibliographic Details
Published in:Pharmacological research 2000-12, Vol.42 (6), p.503-510
Main Authors: Whigham, Leah D, Cook, Mark E, Atkinson, Richard L
Format: Article
Language:English
Subjects:
Adjuvants, Immunologic - pharmacology
Animals
Anticarcinogenic Agents - pharmacology
Arteriosclerosis - drug therapy
Body Composition - drug effects
cancer, body composition, obesity, immune function, heart disease
Humans
Linoleic Acid - pharmacology
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
cited_by cdi_FETCH-LOGICAL-c406t-8f33842588f64dce3e49634ae08d94f3e34d7ce2c4dbe2b3b4ad7817667125153
cites cdi_FETCH-LOGICAL-c406t-8f33842588f64dce3e49634ae08d94f3e34d7ce2c4dbe2b3b4ad7817667125153
container_end_page 510
container_issue 6
container_start_page 503
container_title Pharmacological research
container_volume 42
creator Whigham, Leah D
Cook, Mark E
Atkinson, Richard L
description Conjugated linoleic acid (CLA) is being sold as a panacea that has the capability of reducing or eliminating cancer, preventing heart disease, improving immune function, and altering body composition to treat obesity or build lean body mass. Unfortunately, there has been very little published human research on CLA. This review will examine the literature on CLA and discuss the animal research on which the above claims are made. The limited human studies will be presented with an evaluation of the potential uses of CLA for human health and disease.
doi_str_mv 10.1006/phrs.2000.0735
format article
fullrecord <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_72386784</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><els_id>S1043661800907357</els_id><sourcerecordid>72386784</sourcerecordid><originalsourceid>FETCH-LOGICAL-c406t-8f33842588f64dce3e49634ae08d94f3e34d7ce2c4dbe2b3b4ad7817667125153</originalsourceid><addsrcrecordid>eNp1kE1LxDAQQIMo7rp69Sg9eWtNmjRJvcniFyx40XNIk6nN0jY1aQX_vS274MnTzOHNg3kIXROcEYz53dCEmOUY4wwLWpygNcElTwmR_HTZGU05J3KFLmLcz1TJCD5HK0JwIRnGayS2vt9Pn3oEm7Su9y04k2jj7H3iuqF1Ro_O9zGpfUiaqdN90oBux-YSndW6jXB1nBv08fT4vn1Jd2_Pr9uHXWoY5mMqa0olywspa86sAQqs5JRpwNKWrKZAmRUGcsNsBXlFK6atkERwLkhekIJu0O3BOwT_NUEcVeeigbbVPfgpKpFTyYVkM5gdQBN8jAFqNQTX6fCjCFZLKrWkUksqtaSaD26O5qnqwP7hxzYzIA8AzP99OwgqGge9AesCmFFZ7_5z_wJH_3cG</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>72386784</pqid></control><display><type>article</type><title>Conjugated linoleic acid: implications for human health</title><source>ScienceDirect</source><source>ScienceDirect Freedom Collection</source><creator>Whigham, Leah D ; Cook, Mark E ; Atkinson, Richard L</creator><creatorcontrib>Whigham, Leah D ; Cook, Mark E ; Atkinson, Richard L</creatorcontrib><description>Conjugated linoleic acid (CLA) is being sold as a panacea that has the capability of reducing or eliminating cancer, preventing heart disease, improving immune function, and altering body composition to treat obesity or build lean body mass. Unfortunately, there has been very little published human research on CLA. This review will examine the literature on CLA and discuss the animal research on which the above claims are made. The limited human studies will be presented with an evaluation of the potential uses of CLA for human health and disease.</description><identifier>ISSN: 1043-6618</identifier><identifier>EISSN: 1096-1186</identifier><identifier>DOI: 10.1006/phrs.2000.0735</identifier><identifier>PMID: 11058400</identifier><language>eng</language><publisher>Netherlands: Elsevier Ltd</publisher><subject>Adjuvants, Immunologic - pharmacology ; Animals ; Anticarcinogenic Agents - pharmacology ; Arteriosclerosis - drug therapy ; Body Composition - drug effects ; cancer, body composition, obesity, immune function, heart disease ; Humans ; Linoleic Acid - pharmacology</subject><ispartof>Pharmacological research, 2000-12, Vol.42 (6), p.503-510</ispartof><rights>2000 Academic Press</rights><rights>Copyright 2000 Academic Press.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c406t-8f33842588f64dce3e49634ae08d94f3e34d7ce2c4dbe2b3b4ad7817667125153</citedby><cites>FETCH-LOGICAL-c406t-8f33842588f64dce3e49634ae08d94f3e34d7ce2c4dbe2b3b4ad7817667125153</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://www.sciencedirect.com/science/article/pii/S1043661800907357$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>314,780,784,3549,27924,27925,45780</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/11058400$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Whigham, Leah D</creatorcontrib><creatorcontrib>Cook, Mark E</creatorcontrib><creatorcontrib>Atkinson, Richard L</creatorcontrib><title>Conjugated linoleic acid: implications for human health</title><title>Pharmacological research</title><addtitle>Pharmacol Res</addtitle><description>Conjugated linoleic acid (CLA) is being sold as a panacea that has the capability of reducing or eliminating cancer, preventing heart disease, improving immune function, and altering body composition to treat obesity or build lean body mass. Unfortunately, there has been very little published human research on CLA. This review will examine the literature on CLA and discuss the animal research on which the above claims are made. The limited human studies will be presented with an evaluation of the potential uses of CLA for human health and disease.</description><subject>Adjuvants, Immunologic - pharmacology</subject><subject>Animals</subject><subject>Anticarcinogenic Agents - pharmacology</subject><subject>Arteriosclerosis - drug therapy</subject><subject>Body Composition - drug effects</subject><subject>cancer, body composition, obesity, immune function, heart disease</subject><subject>Humans</subject><subject>Linoleic Acid - pharmacology</subject><issn>1043-6618</issn><issn>1096-1186</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2000</creationdate><recordtype>article</recordtype><recordid>eNp1kE1LxDAQQIMo7rp69Sg9eWtNmjRJvcniFyx40XNIk6nN0jY1aQX_vS274MnTzOHNg3kIXROcEYz53dCEmOUY4wwLWpygNcElTwmR_HTZGU05J3KFLmLcz1TJCD5HK0JwIRnGayS2vt9Pn3oEm7Su9y04k2jj7H3iuqF1Ro_O9zGpfUiaqdN90oBux-YSndW6jXB1nBv08fT4vn1Jd2_Pr9uHXWoY5mMqa0olywspa86sAQqs5JRpwNKWrKZAmRUGcsNsBXlFK6atkERwLkhekIJu0O3BOwT_NUEcVeeigbbVPfgpKpFTyYVkM5gdQBN8jAFqNQTX6fCjCFZLKrWkUksqtaSaD26O5qnqwP7hxzYzIA8AzP99OwgqGge9AesCmFFZ7_5z_wJH_3cG</recordid><startdate>20001201</startdate><enddate>20001201</enddate><creator>Whigham, Leah D</creator><creator>Cook, Mark E</creator><creator>Atkinson, Richard L</creator><general>Elsevier Ltd</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>20001201</creationdate><title>Conjugated linoleic acid: implications for human health</title><author>Whigham, Leah D ; Cook, Mark E ; Atkinson, Richard L</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c406t-8f33842588f64dce3e49634ae08d94f3e34d7ce2c4dbe2b3b4ad7817667125153</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2000</creationdate><topic>Adjuvants, Immunologic - pharmacology</topic><topic>Animals</topic><topic>Anticarcinogenic Agents - pharmacology</topic><topic>Arteriosclerosis - drug therapy</topic><topic>Body Composition - drug effects</topic><topic>cancer, body composition, obesity, immune function, heart disease</topic><topic>Humans</topic><topic>Linoleic Acid - pharmacology</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Whigham, Leah D</creatorcontrib><creatorcontrib>Cook, Mark E</creatorcontrib><creatorcontrib>Atkinson, Richard L</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Pharmacological research</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Whigham, Leah D</au><au>Cook, Mark E</au><au>Atkinson, Richard L</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Conjugated linoleic acid: implications for human health</atitle><jtitle>Pharmacological research</jtitle><addtitle>Pharmacol Res</addtitle><date>2000-12-01</date><risdate>2000</risdate><volume>42</volume><issue>6</issue><spage>503</spage><epage>510</epage><pages>503-510</pages><issn>1043-6618</issn><eissn>1096-1186</eissn><abstract>Conjugated linoleic acid (CLA) is being sold as a panacea that has the capability of reducing or eliminating cancer, preventing heart disease, improving immune function, and altering body composition to treat obesity or build lean body mass. Unfortunately, there has been very little published human research on CLA. This review will examine the literature on CLA and discuss the animal research on which the above claims are made. The limited human studies will be presented with an evaluation of the potential uses of CLA for human health and disease.</abstract><cop>Netherlands</cop><pub>Elsevier Ltd</pub><pmid>11058400</pmid><doi>10.1006/phrs.2000.0735</doi><tpages>8</tpages></addata></record>
fulltext fulltext
identifier ISSN: 1043-6618
ispartof Pharmacological research, 2000-12, Vol.42 (6), p.503-510
issn 1043-6618
1096-1186
language eng
recordid cdi_proquest_miscellaneous_72386784
source ScienceDirect; ScienceDirect Freedom Collection
subjects Adjuvants, Immunologic - pharmacology
Animals
Anticarcinogenic Agents - pharmacology
Arteriosclerosis - drug therapy
Body Composition - drug effects
cancer, body composition, obesity, immune function, heart disease
Humans
Linoleic Acid - pharmacology
title Conjugated linoleic acid: implications for human health
url http://sfxeu10.hosted.exlibrisgroup.com/loughborough?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-06T19%3A16%3A03IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Conjugated%20linoleic%20acid:%20implications%20for%20human%20health&rft.jtitle=Pharmacological%20research&rft.au=Whigham,%20Leah%20D&rft.date=2000-12-01&rft.volume=42&rft.issue=6&rft.spage=503&rft.epage=510&rft.pages=503-510&rft.issn=1043-6618&rft.eissn=1096-1186&rft_id=info:doi/10.1006/phrs.2000.0735&rft_dat=%3Cproquest_cross%3E72386784%3C/proquest_cross%3E%3Cgrp_id%3Ecdi_FETCH-LOGICAL-c406t-8f33842588f64dce3e49634ae08d94f3e34d7ce2c4dbe2b3b4ad7817667125153%3C/grp_id%3E%3Coa%3E%3C/oa%3E%3Curl%3E%3C/url%3E&rft_id=info:oai/&rft_pqid=72386784&rft_id=info:pmid/11058400&rfr_iscdi=true