Increase in Blood Pressure with Enhanced Na+, K+‐ATPase Activity in Stroke‐Prone Spontaneously Hypertensive Rats after 4‐Weeks Intake of Rapeseed Oil as the Sole Dietary Fat

: Twenty stroke‐prone spontaneously hypertensive rats were divided into 2 groups of 10 animals each, and fed a defatted diet and orally administered rapeseed (canola) oil or soybean oil at 10 (w/w)% of the consumed diet once a day for 4 weeks. At the 4th week of administration, the systolic blood pr...

Full description

Saved in:
Bibliographic Details
Published in:Pharmacology & toxicology 2000-09, Vol.87 (3), p.144-148
Main Authors: Naito, Yukiko, Konishi, Chika, Katsumura, Hideo, Ohara, Naoki
Format: Article
Language:English
Subjects:
6-Ketoprostaglandin F1 alpha - analysis
Animals
Biological and medical sciences
Blood Pressure - drug effects
Dietary Fats - administration & dosage
Enzyme-Linked Immunosorbent Assay
Fatty Acids, Monounsaturated
Food toxicology
Male
Medical sciences
Muscle, Smooth, Vascular - drug effects
Muscle, Smooth, Vascular - enzymology
Plant Oils - administration & dosage
Plant Oils - pharmacology
Rapeseed Oil
Rats
Rats, Inbred SHR
Sodium-Potassium-Exchanging ATPase - metabolism
Thromboxane B2 - analysis
Toxicology
Citations: Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:: Twenty stroke‐prone spontaneously hypertensive rats were divided into 2 groups of 10 animals each, and fed a defatted diet and orally administered rapeseed (canola) oil or soybean oil at 10 (w/w)% of the consumed diet once a day for 4 weeks. At the 4th week of administration, the systolic blood pressure in the canola oil group was higher (235±2 mmHg, mean±S.E.M., N=10) than that in the soybean oil group (225±4 mmHg, N=10, P
ISSN:0901-9928
1600-0773
DOI:10.1034/j.1600-0773.2000.pto870308.x