Fatty Liver in Obesity: Relation to Doppler Perfusion Index Measurement of the Liver

Background: The correlation of clinical and laboratory findings with various imaging techniques in obese patients is difficult. Colour duplex Doppler is of particularly limited value in fat individuals. The Doppler Perfusion Index (DPI) measures the ratio of hepatic arterial to total liver blood flo...

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Bibliographic Details
Published in:Scandinavian journal of gastroenterology 2000, Vol.35 (9), p.976-980
Main Authors: KAKKOS, S. K, YARMENITIS, S. D, TSAMANDAS, A. C, GOGOS, C. A, KALFARENTZOS, F
Format: Article
Language:English
Subjects:
Adult
Aspartate Aminotransferases - blood
Biological and medical sciences
Biopsy
Body Mass Index
Case-Control Studies
Fatty Liver - diagnosis
Fatty Liver - diagnostic imaging
Fatty Liver - etiology
Female
Humans
Liver - pathology
Liver Circulation
Liver Function Tests
Male
Medical sciences
Metabolic diseases
Obesity
Obesity - complications
Obesity - pathology
Prospective Studies
Triglycerides - blood
Ultrasonography, Doppler, Color
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Summary:Background: The correlation of clinical and laboratory findings with various imaging techniques in obese patients is difficult. Colour duplex Doppler is of particularly limited value in fat individuals. The Doppler Perfusion Index (DPI) measures the ratio of hepatic arterial to total liver blood flow and seems to be more accurate in the study of hepatic hemodynamics. The aim of the present study was to investigate the clinical use of DPI measurement of the liver in obesity. Methods: In the present prospective, open study we evaluated the DPI in 41 obese patients (body mass index (BMI) > 30 kg/m2) and 18 volunteers with normal or slightly increased weight. Thirty patients of the study group underwent liver biopsy during bariatric surgery. In these patients liver histology was assessed and age, BMI, waist to hip ratio (WHR), DPI, liver function tests and serum triglycerides were measured. Results: Obese patients had significantly (P
ISSN:0036-5521
1502-7708
DOI:10.1080/003655200750023066