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Sarcomatoid carcinoma of the pyriform sinus with brain and subcutaneous metastases : an unusual metastatic spread pattern
A 63-year-old man presented a polypoid tumor in the laryngeal space involving the right pyriform fossa. The patient underwent a total laryngectomy with bilateral functional neck dissection, and the diagnosis of sarcomatoid carcinoma with malignant fibrous histiocytoma-like stroma was established. Th...
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Published in: | European archives of oto-rhino-laryngology 2000, Vol.257 (8), p.445-448 |
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creator | HARDISSON, David DE DIEGO, Juan Ignacio PRIM, Maria Pilar |
description | A 63-year-old man presented a polypoid tumor in the laryngeal space involving the right pyriform fossa. The patient underwent a total laryngectomy with bilateral functional neck dissection, and the diagnosis of sarcomatoid carcinoma with malignant fibrous histiocytoma-like stroma was established. The tumor showed an uncommon behavior, with distant metastases to the brain and to the subcutaneous tissue of the abdominal wall. The patient died 1 year after the development of the metastases. Despite its polypoid pattern of growth, sarcomatoid carcinoma of the larynx may behave very aggressively. It is important for clinicians to be aware of the possibility of distant subcutaneous and brain metastases in sarcomatoid tumors of the laryngeal space. If such metastases develop, the prognosis is ominous, with an average life expectancy of 3 months. |
doi_str_mv | 10.1007/s004050000257 |
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The patient underwent a total laryngectomy with bilateral functional neck dissection, and the diagnosis of sarcomatoid carcinoma with malignant fibrous histiocytoma-like stroma was established. The tumor showed an uncommon behavior, with distant metastases to the brain and to the subcutaneous tissue of the abdominal wall. The patient died 1 year after the development of the metastases. Despite its polypoid pattern of growth, sarcomatoid carcinoma of the larynx may behave very aggressively. It is important for clinicians to be aware of the possibility of distant subcutaneous and brain metastases in sarcomatoid tumors of the laryngeal space. If such metastases develop, the prognosis is ominous, with an average life expectancy of 3 months.</description><identifier>ISSN: 0937-4477</identifier><identifier>EISSN: 1434-4726</identifier><identifier>DOI: 10.1007/s004050000257</identifier><identifier>PMID: 11073196</identifier><language>eng</language><publisher>Berlin: Springer</publisher><subject>Abdominal Neoplasms - diagnosis ; Abdominal Neoplasms - secondary ; Biological and medical sciences ; Brain Neoplasms - diagnosis ; Brain Neoplasms - secondary ; Carcinoma - diagnosis ; Carcinoma - secondary ; Carcinoma - surgery ; Fatal Outcome ; Humans ; Laryngeal Neoplasms - pathology ; Laryngeal Neoplasms - surgery ; Laryngectomy ; Magnetic Resonance Imaging ; Male ; Medical sciences ; Middle Aged ; Neck Dissection ; Otorhinolaryngology (head neck, general aspects and miscellaneous) ; Otorhinolaryngology. 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The patient underwent a total laryngectomy with bilateral functional neck dissection, and the diagnosis of sarcomatoid carcinoma with malignant fibrous histiocytoma-like stroma was established. The tumor showed an uncommon behavior, with distant metastases to the brain and to the subcutaneous tissue of the abdominal wall. The patient died 1 year after the development of the metastases. Despite its polypoid pattern of growth, sarcomatoid carcinoma of the larynx may behave very aggressively. It is important for clinicians to be aware of the possibility of distant subcutaneous and brain metastases in sarcomatoid tumors of the laryngeal space. If such metastases develop, the prognosis is ominous, with an average life expectancy of 3 months.</description><subject>Abdominal Neoplasms - diagnosis</subject><subject>Abdominal Neoplasms - secondary</subject><subject>Biological and medical sciences</subject><subject>Brain Neoplasms - diagnosis</subject><subject>Brain Neoplasms - secondary</subject><subject>Carcinoma - diagnosis</subject><subject>Carcinoma - secondary</subject><subject>Carcinoma - surgery</subject><subject>Fatal Outcome</subject><subject>Humans</subject><subject>Laryngeal Neoplasms - pathology</subject><subject>Laryngeal Neoplasms - surgery</subject><subject>Laryngectomy</subject><subject>Magnetic Resonance Imaging</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Middle Aged</subject><subject>Neck Dissection</subject><subject>Otorhinolaryngology (head neck, general aspects and miscellaneous)</subject><subject>Otorhinolaryngology. Stomatology</subject><subject>Tomography, X-Ray Computed</subject><subject>Tumors</subject><issn>0937-4477</issn><issn>1434-4726</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2000</creationdate><recordtype>article</recordtype><recordid>eNpVkE1LJDEQhoMoOqsevUoO4q3XpJN0Jd5EdBUG9qCem-p0GiP9ZZJG5t8bmRGxKKivp4riJeSMs7-cMbiKjEmmWLZSwR5ZcSlkIaGs9smKGQGFlABH5E-Mb5lR0ohDcsQ5A8FNtSKbJwx2GjBNvqU2537MFZ06ml4dnTfBd1MYaPTjEumHT6-0CehHimNL49LYJeHopjwbXMKY3UV6nad0yQsL9t_95C2Nc3DY0hlTcmE8IQcd9tGd7uIxebm_e759KNb__z3e3qwLK7hOhWwaVUFXoUZsUbkSnFWty10BjW5YC6AlWg1OadSGcWZ0V0pQ2ladaUAck8vt3TlM74uLqR58tK7vt4_XUApjTMkyWGxBG6YYg-vqOfgBw6bmrP7Suv6ldebPd4eXZnDtD70TNwMXOwCjxb4LOFoffzjFQZlSfAJba4jG</recordid><startdate>2000</startdate><enddate>2000</enddate><creator>HARDISSON, David</creator><creator>DE DIEGO, Juan Ignacio</creator><creator>PRIM, Maria Pilar</creator><general>Springer</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>2000</creationdate><title>Sarcomatoid carcinoma of the pyriform sinus with brain and subcutaneous metastases : an unusual metastatic spread pattern</title><author>HARDISSON, David ; DE DIEGO, Juan Ignacio ; PRIM, Maria Pilar</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c318t-4bb567f6a8aada5e27ec5debb537b8b0d7784ac87e58a8901098f24758c6f9b73</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2000</creationdate><topic>Abdominal Neoplasms - diagnosis</topic><topic>Abdominal Neoplasms - secondary</topic><topic>Biological and medical sciences</topic><topic>Brain Neoplasms - diagnosis</topic><topic>Brain Neoplasms - secondary</topic><topic>Carcinoma - diagnosis</topic><topic>Carcinoma - secondary</topic><topic>Carcinoma - surgery</topic><topic>Fatal Outcome</topic><topic>Humans</topic><topic>Laryngeal Neoplasms - pathology</topic><topic>Laryngeal Neoplasms - surgery</topic><topic>Laryngectomy</topic><topic>Magnetic Resonance Imaging</topic><topic>Male</topic><topic>Medical sciences</topic><topic>Middle Aged</topic><topic>Neck Dissection</topic><topic>Otorhinolaryngology (head neck, general aspects and miscellaneous)</topic><topic>Otorhinolaryngology. Stomatology</topic><topic>Tomography, X-Ray Computed</topic><topic>Tumors</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>HARDISSON, David</creatorcontrib><creatorcontrib>DE DIEGO, Juan Ignacio</creatorcontrib><creatorcontrib>PRIM, Maria Pilar</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>European archives of oto-rhino-laryngology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>HARDISSON, David</au><au>DE DIEGO, Juan Ignacio</au><au>PRIM, Maria Pilar</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Sarcomatoid carcinoma of the pyriform sinus with brain and subcutaneous metastases : an unusual metastatic spread pattern</atitle><jtitle>European archives of oto-rhino-laryngology</jtitle><addtitle>Eur Arch Otorhinolaryngol</addtitle><date>2000</date><risdate>2000</risdate><volume>257</volume><issue>8</issue><spage>445</spage><epage>448</epage><pages>445-448</pages><issn>0937-4477</issn><eissn>1434-4726</eissn><abstract>A 63-year-old man presented a polypoid tumor in the laryngeal space involving the right pyriform fossa. The patient underwent a total laryngectomy with bilateral functional neck dissection, and the diagnosis of sarcomatoid carcinoma with malignant fibrous histiocytoma-like stroma was established. The tumor showed an uncommon behavior, with distant metastases to the brain and to the subcutaneous tissue of the abdominal wall. The patient died 1 year after the development of the metastases. Despite its polypoid pattern of growth, sarcomatoid carcinoma of the larynx may behave very aggressively. It is important for clinicians to be aware of the possibility of distant subcutaneous and brain metastases in sarcomatoid tumors of the laryngeal space. If such metastases develop, the prognosis is ominous, with an average life expectancy of 3 months.</abstract><cop>Berlin</cop><pub>Springer</pub><pmid>11073196</pmid><doi>10.1007/s004050000257</doi><tpages>4</tpages></addata></record> |
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subjects | Abdominal Neoplasms - diagnosis Abdominal Neoplasms - secondary Biological and medical sciences Brain Neoplasms - diagnosis Brain Neoplasms - secondary Carcinoma - diagnosis Carcinoma - secondary Carcinoma - surgery Fatal Outcome Humans Laryngeal Neoplasms - pathology Laryngeal Neoplasms - surgery Laryngectomy Magnetic Resonance Imaging Male Medical sciences Middle Aged Neck Dissection Otorhinolaryngology (head neck, general aspects and miscellaneous) Otorhinolaryngology. Stomatology Tomography, X-Ray Computed Tumors |
title | Sarcomatoid carcinoma of the pyriform sinus with brain and subcutaneous metastases : an unusual metastatic spread pattern |
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