Isoflurane, desflurane and sevoflurane for carotid endarterectomy

After carotid endarterectomy under general anaesthesia, the rapid elimination of desflurane and sevoflurane may allow earlier postoperative neurological assessment than after the use of isoflurane. However, desflurane may be associated with tachycardia and hypertension and may therefore increase car...

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Bibliographic Details
Published in:Anaesthesia 2000-11, Vol.55 (11), p.1052-1057
Main Authors: Umbrain, V., Keeris, J., D'Haese, J., Verborgh, C., Debing, E., Van den Brande, P., Camu, F.
Format: Article
Language:English
Subjects:
Aged
Anaesthetic agents
Anesthesia Recovery Period
Anesthetics, Inhalation - pharmacology
Anesthetics. Neuromuscular blocking agents
Biological and medical sciences
carotid endarterectomy
Cognition - drug effects
Desflurane
Endarterectomy, Carotid
Female
Haemodynamics. Recovery. Equipment
Hemodynamics - drug effects
Humans
isoflurane
Isoflurane - analogs & derivatives
Isoflurane - pharmacology
Length of Stay
Male
Medical sciences
Methyl Ethers - pharmacology
Middle Aged
Movement - drug effects
Neuropharmacology
oesophageal Doppler monitor
Pharmacology. Drug treatments
Postoperative Complications
Sevoflurane
Surgery
vascular
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Summary:After carotid endarterectomy under general anaesthesia, the rapid elimination of desflurane and sevoflurane may allow earlier postoperative neurological assessment than after the use of isoflurane. However, desflurane may be associated with tachycardia and hypertension and may therefore increase cardiovascular risk. We investigated haemodynamic and recovery characteristics in patients scheduled for carotid endarterectomy who were anaesthetised with isoflurane, sevoflurane or desflurane. No significant peri‐operative differences were noted in cardiac index or ST segment analysis. The times to extubation, movement on command and consciousness were shorter after desflurane and sevoflurane than after isoflurane anaesthesia. Postoperative pain, nausea, vomiting and shivering were similar in the three study groups.
ISSN:0003-2409
1365-2044
DOI:10.1046/j.1365-2044.2000.01617.x