Cyclopeptide Alkaloids from Paliurus ramossisimus

Seven zizyphine A-type cyclopeptide alkaloids were isolated from the roots of Paliurus ramossisimus by the combination of centrifugal partition chromatography and conventional separation methods. The novel structures of paliurines A-F (1-6) were characterized and established on the basis of MS and e...

Full description

Saved in:
Bibliographic Details
Published in:Journal of natural products (Washington, D.C.) D.C.), 2000-10, Vol.63 (10), p.1338-1343
Main Authors: LIN, Hui-yi, CHEN, Chung-Hsiung, YOU, Bih-Jing, LIU, Karin C. S. Chen, LEE, Shoei-Sheng
Format: Article
Language:English
Subjects:
Alkaloids - chemistry
Alkaloids - isolation & purification
Biological and medical sciences
General pharmacology
Magnetic Resonance Spectroscopy
Medical sciences
Peptides, Cyclic - chemistry
Peptides, Cyclic - isolation & purification
Pharmacognosy. Homeopathy. Health food
Pharmacology. Drug treatments
Plants, Medicinal - chemistry
Rosales - chemistry
Taiwan
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Seven zizyphine A-type cyclopeptide alkaloids were isolated from the roots of Paliurus ramossisimus by the combination of centrifugal partition chromatography and conventional separation methods. The novel structures of paliurines A-F (1-6) were characterized and established on the basis of MS and elaborate NMR spectral analyses. Terminal dipeptide stereochemistry was confirmed by correlation with the synthetic dipeptides via comparison of their (13)C NMR data.
ISSN:0163-3864
1520-6025
DOI:10.1021/np000136a