The Utility of Polysporin Ointment in the Eradication of Methicillin‐Resistant Staphylococcus aureus Colonization: A Pilot Study

We evaluated the efficacy of an ointment containing bacitracin, polymyxin B, and gramicidin for the eradication of colonization by methicillin‐resistant Staphylococcus aureus in 11 medical patients, 10 (91%) of whom had previously failed a 1‐week course of topical mupirocin. Mupirocin resistance was...

Full description

Saved in:
Bibliographic Details
Published in:Infection control and hospital epidemiology 2000-10, Vol.21 (10), p.653-655
Main Authors: Fung, Scott, O’Grady, Sharon, Kennedy, Catharine, Dedier, Helen, Campbell, Iivi, Conly, John
Format: Article
Language:English
Subjects:
Aged
Aged, 80 and over
Anti-Infective Agents, Local - pharmacology
Antibacterial agents
Antibiotics. Antiinfectious agents. Antiparasitic agents
Antimicrobials
Axilla
Bacitracin - pharmacology
Biological and medical sciences
Colonization
Concise Communications
Decolonization
Drug Combinations
Drug Therapy, Combination - pharmacology
Female
Gramicidin - pharmacology
Humans
Male
Medical sciences
Methicillin Resistance
Methicillin resistant staphylococcus aureus
Microbial colonization
Middle Aged
Mupirocin - pharmacology
Nursing
Ointments
Parent teacher organizations
Pharmacology. Drug treatments
Pilot Projects
Polymyxin B - pharmacology
Polymyxins
Pressure ulcer
Staphylococcus aureus
Staphylococcus aureus - drug effects
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:We evaluated the efficacy of an ointment containing bacitracin, polymyxin B, and gramicidin for the eradication of colonization by methicillin‐resistant Staphylococcus aureus in 11 medical patients, 10 (91%) of whom had previously failed a 1‐week course of topical mupirocin. Mupirocin resistance was documented in 5 (45%) of 11 patients. Successful decolonization was achieved in 9 (82%) of 11 patients (based on 2 months of follow‐up).
ISSN:0899-823X
1559-6834
DOI:10.1086/501709