Somatostatinoma of the Ampulla of vater in celiac sprue

The increased incidence of gastrointestinal lymphoma and adenocarcinoma in patients with celiac sprue is well recognized, with 10% to 15% developing a gastrointestinal malignancy. Somatostatinomas are rare neuroendocrine tumors that occur most commonly within the pancreatic head or duodenum. Althoug...

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Bibliographic Details
Published in:Journal of gastrointestinal surgery 2000-07, Vol.4 (4), p.388-391
Main Authors: James Frick, E., Kralstein, Jeffrey R., Scarlato, Michael, Hoover, Herbert C.
Format: Article
Language:English
Subjects:
Adult
Ampulla of Vater - pathology
Biopsy
Celiac disease
Celiac Disease - complications
Common Bile Duct Neoplasms - diagnosis
Diet
Endoscopy, Digestive System
Female
Follow-Up Studies
Humans
Incidence
Laparotomy
neoplasms
Small intestine
somatostatinoma
Somatostatinoma - diagnosis
Vater's ampulla
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Summary:The increased incidence of gastrointestinal lymphoma and adenocarcinoma in patients with celiac sprue is well recognized, with 10% to 15% developing a gastrointestinal malignancy. Somatostatinomas are rare neuroendocrine tumors that occur most commonly within the pancreatic head or duodenum. Although fewer than 100 cases have been reported, somatostatinomas are often associated with multiple endocrine neoplasia-1 syndrome and von Recklinghausen's disease. The unusual case of a 43-year-old woman with celiac sprue in which a somatostatinoma involving the ampulla of Vater was identified and resected is presented. To our knowledge, somatostatinomas have not been previously reported in patients with celiac sprue.
ISSN:1091-255X
1873-4626
DOI:10.1016/S1091-255X(00)80017-7