Features and trends in Helicobacter pylori antibiotic resistance in Lisbon area, Portugal (1990–1999)

The features of Helicobacter pylori antibiotic resistance in Lisbon from 1990 to 1999 were studied. Overall resistance rates to amoxycillin, tetracycline, metronidazole, clarithromycin and ciprofloxacin were 0, 0, 30.6, 19.0 and 9.6%, respectively. The incidence of resistance to clarithromycin was m...

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Bibliographic Details
Published in:Journal of antimicrobial chemotherapy 2000-12, Vol.46 (6), p.1029-1031
Main Authors: Cabrita, J., Oleastro, M., Matos, R., Manhente, A., Cabral, J., Barros, R., Lopes, A. I., Ramalho, P., Neves, B. C., Guerreiro, A. S.
Format: Article
Language:English
Subjects:
Adolescent
Adult
Aged
Aged, 80 and over
Antibacterial agents
Antibiotics. Antiinfectious agents. Antiparasitic agents
Bacteriology
Biological and medical sciences
Child
Child, Preschool
Drug Resistance, Microbial
Epidemiology
Female
Fundamental and applied biological sciences. Psychology
Helicobacter pylori
Helicobacter pylori - drug effects
Humans
Male
Medical sciences
Microbiology
Middle Aged
Pharmacology. Drug treatments
Portugal
Portugal, Lisbon
Time Factors
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Summary:The features of Helicobacter pylori antibiotic resistance in Lisbon from 1990 to 1999 were studied. Overall resistance rates to amoxycillin, tetracycline, metronidazole, clarithromycin and ciprofloxacin were 0, 0, 30.6, 19.0 and 9.6%, respectively. The incidence of resistance to clarithromycin was much higher in isolates from children (44.8%) than adults (14.6%). For metronidazole, the contrary was observed (children: 19.0%, adults: 32.3%). Ciprofloxacin-resistant isolates were all from adult patients. Concerning the adult population, the resistance rate to metronidazole showed a slight increase during the decade, while for clarithromycin and ciprofloxacin a significant increase was observed (4.6 to 22.0% and 0 to 20.9%, respectively).
ISSN:0305-7453
1460-2091
1460-2091
DOI:10.1093/jac/46.6.1029