Hypersensitivity reactions following laminaria placement

Laminaria tents are commonly placed intracervically prior to elective termination of pregnancy. Three women, each of whom had undergone at least one previous abortion in which a laminaria was utilized, developed hypersensitivity reactions following laminaria placement. The reactions included urticar...

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Bibliographic Details
Published in:Contraception (Stoneham) 2000-08, Vol.62 (2), p.105-106
Main Authors: Chanda, Melanie, Mackenzie, Paul, Day, James H
Format: Article
Language:English
Subjects:
Abortion, Induced - methods
Adult
Allergy
Anaphylaxis
Anti-Allergic Agents - therapeutic use
Anti-Inflammatory Agents - therapeutic use
Biological and medical sciences
Bronchodilator Agents - therapeutic use
Canada
Diphenhydramine - therapeutic use
Drug toxicity and drugs side effects treatment
Epinephrine - therapeutic use
Female
Humans
Hypersensitivity - drug therapy
Hypersensitivity - etiology
Induced abortion
Laminaria
Medical sciences
Miscellaneous (drug allergy, mutagens, teratogens...)
Pharmacology. Drug treatments
Prednisone - therapeutic use
Pregnancy
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Summary:Laminaria tents are commonly placed intracervically prior to elective termination of pregnancy. Three women, each of whom had undergone at least one previous abortion in which a laminaria was utilized, developed hypersensitivity reactions following laminaria placement. The reactions included urticaria, angioedema and respiratory distress. All responded to removal of the laminaria and administration of either diphenhydramine, prednisone, inhaled bronchodilators or subcutaneous epinephrine. One of the women subsequently underwent skin testing and was positive to laminaria. Patients undergoing laminaria placement may manifest a Type I reaction, IgE-mediated sensitivity. Providers should counsel patients with histories of multiple previous laminaria insertions about this possibility, have alternative methods of cervical dilation available, and be able to promptly recognize and treat reactions when they occur.
ISSN:0010-7824
1879-0518
DOI:10.1016/S0010-7824(00)00145-1