Vitamin D-Deficiency Rickets in Adopted Children From the Former Soviet Union: An Uncommon Problem With Unusual Clinical and Biochemical Features

Rickets is an unusual disorder in international adoptees. Three international adoptees from the former Soviet Union recently presented with rickets. Their clinical and laboratory presentations were atypical, reflecting circumstances unique to children adopted from orphanages in the former Soviet Uni...

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Bibliographic Details
Published in:Pediatrics (Evanston) 2000-12, Vol.106 (6), p.1484-1489
Main Authors: Reeves, Grafton D, Bachrach, Steven, Carpenter, Thomas O, Mackenzie, William G
Format: Article
Language:English
Subjects:
Adopted children
Adoption - ethnology
Biological and medical sciences
Case studies
Child, Preschool
Children, Adopted
Diseases of the osteoarticular system
Female
Femur - diagnostic imaging
Fibula - diagnostic imaging
Hand - diagnostic imaging
Health aspects
Humans
Male
Medical sciences
Miscellaneous. Osteoarticular involvement in other diseases
Orphanages
Radiography
Rickets
Rickets - diagnosis
Rickets - drug therapy
Rickets - ethnology
Tibia - diagnostic imaging
United States
USSR - ethnology
Vitamin D - therapeutic use
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Summary:Rickets is an unusual disorder in international adoptees. Three international adoptees from the former Soviet Union recently presented with rickets. Their clinical and laboratory presentations were atypical, reflecting circumstances unique to children adopted from orphanages in the former Soviet Union and the early initiation of vitamin D therapy. In these children, radiographs of the long bones were diagnostic when the classically diagnostic biochemical parameters, calcium and 25OHD(3) levels, were normal.
ISSN:0031-4005
1098-4275
DOI:10.1542/peds.106.6.1484