Therapeutic effects of oral zinc in acute and persistent diarrhea in children in developing countries : pooled analysis of randomized controlled trials

Zinc deficiency is prevalent in children in developing countries. Supplemental zinc provides therapeutic benefits in diarrhea. We sought to measure the effect of supplemental zinc given with oral rehydration therapy during recovery from acute or persistent diarrhea. We conducted pooled analyses incl...

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Bibliographic Details
Published in:The American journal of clinical nutrition 2000-12, Vol.72 (6), p.1516-1522
Main Authors: Bhutta, Z A, Bird, S M, Black, R E, Brown, K H, Gardner, J M, Hidayat, A, Khatun, F, Martorell, R, Ninh, N X, Penny, M E, Rosado, J L, Roy, S K, Ruel, M, Sazawal, S, Shankar, A
Format: Article
Language:English
Subjects:
Acute Disease
Administration, Oral
Biological and medical sciences
Child, Preschool
Children & youth
Developing Countries
Diarrhea
Diarrhea - drug therapy
Drug therapy
Female
Fluid Therapy
Gastroenterology. Liver. Pancreas. Abdomen
Humans
Infant
LDCs
Logistic Models
Male
Malnutrition
Medical sciences
Other diseases. Semiology
Randomized Controlled Trials as Topic
Stomach. Duodenum. Small intestine. Colon. Rectum. Anus
Tropical medicine
Zinc
Zinc - administration & dosage
Zinc - blood
Zinc - deficiency
Zinc - therapeutic use
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Description
Summary:Zinc deficiency is prevalent in children in developing countries. Supplemental zinc provides therapeutic benefits in diarrhea. We sought to measure the effect of supplemental zinc given with oral rehydration therapy during recovery from acute or persistent diarrhea. We conducted pooled analyses including all available published and unpublished randomized controlled trials of the effects of supplementary oral zinc in children aged
ISSN:0002-9165
1938-3207
DOI:10.1093/ajcn/72.6.1516