A long-term survivor of metastatic gastric cancer treated by chemotherapy: case report

A long-term survivor of advanced gastric cancer with multiple metastases to the liver treated by chemotherapy is described. Chemotherapy comprising a combination of uracil and tegafur with mitomycin C achieved a complete response in the patient which lasted for approximately four years. Four years a...

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Bibliographic Details
Published in:Japanese journal of clinical oncology 1991-08, Vol.21 (4), p.299-305
Main Authors: Nagase, K, Ohtsu, A, Saito, Y, Saito, M, Ikeya, S, Ishii, N, Nakayama, H, Hoshino, E, Sugai, Y, Wachi, E
Format: Article
Language:English
Subjects:
Adenocarcinoma - diagnostic imaging
Adenocarcinoma - drug therapy
Adenocarcinoma - pathology
Adenocarcinoma - secondary
Aged
Antineoplastic Combined Chemotherapy Protocols - therapeutic use
Humans
Liver Neoplasms - secondary
Male
Radiography
Skin Neoplasms - secondary
Stomach Neoplasms - diagnostic imaging
Stomach Neoplasms - drug therapy
Stomach Neoplasms - pathology
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Description
Summary:A long-term survivor of advanced gastric cancer with multiple metastases to the liver treated by chemotherapy is described. Chemotherapy comprising a combination of uracil and tegafur with mitomycin C achieved a complete response in the patient which lasted for approximately four years. Four years after initiation of the chemotherapy, a unique form of cancer recurrence occurred on the skin, showing infiltrative erythema. Cancer metastases developed further despite more treatment, and the patient died of generalized metastasis four years six months after the initiation of chemotherapy. It is significant that, at autopsy, no cancer cells were revealed in the primary lesion or in the liver which had been present before the initial chemotherapy.
ISSN:0368-2811
1465-3621
1465-3621
DOI:10.1093/oxfordjournals.jjco.a039475