Drawbacks of GENEHUNTER for larger pedigrees: Application to panic disorder

Large pedigrees can pose a problem for GENEHUNTER linkage analysis software. Differences in two‐point and multipoint lodscores were observed when comparing GENEHUNTER to other linkage software. Careful consideration must be given when selecting linkage analysis programs. Am. J. Med. Genet. (Neuropsy...

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Bibliographic Details
Published in:American journal of medical genetics 2000-12, Vol.96 (6), p.781-783
Main Authors: Goedken, R., Ludington, E., Crowe, R., Fyer, A.J., Hodge, S.E., Knowles, J.A., Vieland, V.J., Weissman, M.M
Format: Article
Language:English
Subjects:
Chromosome Mapping
Genetic Linkage
Genetic Markers
Humans
linkage analysis
linkage software
Lod Score
lodscore
Panic Disorder - genetics
Pedigree
pedigrees
Software
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Summary:Large pedigrees can pose a problem for GENEHUNTER linkage analysis software. Differences in two‐point and multipoint lodscores were observed when comparing GENEHUNTER to other linkage software. Careful consideration must be given when selecting linkage analysis programs. Am. J. Med. Genet. (Neuropsychiatr. Genet.) 96:781–783, 2000. © 2000 Wiley‐Liss, Inc.
ISSN:0148-7299
1096-8628
DOI:10.1002/1096-8628(20001204)96:6<781::AID-AJMG17>3.0.CO;2-J