Photomodulation of enzymes

The photomodulation of enzymes involves the activation and inactivation of enzyme reactions by UV and visible light. Enzymes or their reactions may be affected directly or indirectly. Direct effects involve photoproduction of a substrate, photodissociation of an inhibitor, photochemistry of protein...

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Bibliographic Details
Published in:Journal of photochemistry and photobiology. B, Biology Biology, 1991-07, Vol.10 (1-2), p.3-22
Main Authors: HUG, D. H, HUNTER, J. K
Format: Article
Language:English
Subjects:
Animals
Arteries - enzymology
Biological and medical sciences
Enzyme Activation
Enzymes - radiation effects
Fundamental and applied biological sciences. Psychology
Humans
Light
Plants - enzymology
Skin - enzymology
Tissues, organs and organisms biophysics
Ultraviolet Rays
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Summary:The photomodulation of enzymes involves the activation and inactivation of enzyme reactions by UV and visible light. Enzymes or their reactions may be affected directly or indirectly. Direct effects involve photoproduction of a substrate, photodissociation of an inhibitor, photochemistry of protein amino acids, irradiation of a chromophore and irradiation of an enzyme substrate. Indirect effects involve gene expression, phytochrome and other photoreceptors which are not part of the enzyme, protein synthesis, membranes and photosynthesis. Photoactivation of enzymes is related to photocarcinogenesis, photomorphogenesis of plants, primary effects or side effects of phototherapy, deoxyribose nucleic acid (DNA) repair and many other aspects of biology and medicine. Model systems may contribute to the knowledge of protein chemistry and medicinal chemistry.
ISSN:1011-1344
1873-2682
DOI:10.1016/1011-1344(91)80208-Y