Childhood and adolescent predictors of schizophrenia in the Northern Finland 1966 birth cohort--a descriptive life-span model

Subtle motor, emotional, cognitive and behavioral abnormalities are often present in apparently healthy children and adolescents who later develop schizophrenia. This suggests that some aspects of causation are established long before psychosis is manifest. We aim to develop a descriptive model of t...

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Bibliographic Details
Published in:European archives of psychiatry and clinical neuroscience 2000-12, Vol.250 (6), p.311-319
Main Authors: Isohanni, M, Jones, P, Kemppainen, L, Croudace, T, Isohanni, I, Veijola, J, Räsänen, S, Wahlberg, K E, Tienari, P, Rantakallio, P
Format: Article
Language:English
Subjects:
Adolescent
Adult
Birth weight
Child
Child Behavior Disorders - diagnosis
Child Behavior Disorders - epidemiology
Child Behavior Disorders - etiology
Cohort Studies
Female
Finland
Humans
Male
Personality Development
Pregnancy
Prenatal Exposure Delayed Effects
Risk Factors
Schizophrenia
Schizophrenia - diagnosis
Schizophrenia - epidemiology
Schizophrenia - etiology
Schizotypal Personality Disorder - diagnosis
Schizotypal Personality Disorder - epidemiology
Schizotypal Personality Disorder - etiology
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Summary:Subtle motor, emotional, cognitive and behavioral abnormalities are often present in apparently healthy children and adolescents who later develop schizophrenia. This suggests that some aspects of causation are established long before psychosis is manifest. We aim to develop a descriptive model of the factors contributing to the development of schizophrenia. Our main focus is on genetic factors, pregnancy and delivery complications, early development and scholastic performance. This is done by reviewing the Northern Finland 1966 Birth Cohort, its scientific activities (publications and work in progress) and selected literature.
ISSN:0940-1334
1433-8491
DOI:10.1007/s004060070006