Otolaryngologic manifestations of small vessel vasculitis

Objective: The aim of the present study is to review the clinical manifestations associated with small vessel vasculitis (SVV) as they pertain to the head and neck region. Methods: A retrospective analysis was performed, including 34 individuals that filled the American College of Rheumatology crite...

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Bibliographic Details
Published in:Auris, nasus, larynx nasus, larynx, 2002-10, Vol.29 (4), p.353-356
Main Authors: Metaxaris, George, Prokopakis, Emmanuel P, Karatzanis, Alexander D, Sakelaris, George, Heras, Panagiotis, Velegrakis, George A, Helidonis, Emmanuel S
Format: Article
Language:English
Subjects:
Antibodies, Antineutrophil Cytoplasmic - immunology
Churg-Strauss Syndrome - complications
Churg-Strauss Syndrome - immunology
ENT manifestations
Fever - complications
Fever - epidemiology
Granulomatosis with Polyangiitis - complications
Granulomatosis with Polyangiitis - immunology
Humans
Nasal Obstruction - complications
Nasal Obstruction - epidemiology
Polyarteritis Nodosa - complications
Polyarteritis Nodosa - immunology
Retrospective Studies
Sinusitis - complications
Sinusitis - epidemiology
Small vessel vasculitis
Wegener's granulomatosis
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Summary:Objective: The aim of the present study is to review the clinical manifestations associated with small vessel vasculitis (SVV) as they pertain to the head and neck region. Methods: A retrospective analysis was performed, including 34 individuals that filled the American College of Rheumatology criteria for the diagnosis of necrotizing vasculitis. Seven patients were classified as suffering from Wegener's granulomatosis (WG), 18 from microscopic polyangitis (MPA), and the remaining 19 were unclassified (unclassified small vessel vasculitis, USVV). Results: The percentage of ENT manifestations in the early clinical picture of WG patients was 86%, dropping to 44.5 and 22% for MPA and USVV patients, respectively. The overall percentage of ENT manifestations for SVV patients in their initial clinical profile was 47%. Conclusion: The results of our investigation highlight the importance of an ENT clinical examination as a guide for diagnosis of an important percentage of SVV patients.
ISSN:0385-8146
1879-1476
DOI:10.1016/S0385-8146(02)00062-7