Autotransfusion during extracorporeal membrane oxygenation

To reduce allogeneic blood transfusion requirements during extracorporeal membrane oxygenation (ECMO) we evaluated an autotransfusion device which processes and retransfuses erythrocytes of changed ECMO-systems. We studied 10 elective changes of ECMO-systems in 7 patients. Hemoglobin levels, the amo...

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Bibliographic Details
Published in:International journal of artificial organs 2000-12, Vol.23 (12), p.840-844
Main Authors: Tolksdorf, B, Schmeck, J, Osika, A, Bender, H J, Quintel, M
Format: Article
Language:English
Subjects:
Adult
Blood Transfusion, Autologous
Equipment Design
Extracorporeal Membrane Oxygenation - instrumentation
Extracorporeal Membrane Oxygenation - methods
Hemoglobins
Humans
Interleukins - blood
Tumor Necrosis Factor-alpha - metabolism
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Summary:To reduce allogeneic blood transfusion requirements during extracorporeal membrane oxygenation (ECMO) we evaluated an autotransfusion device which processes and retransfuses erythrocytes of changed ECMO-systems. We studied 10 elective changes of ECMO-systems in 7 patients. Hemoglobin levels, the amount of retransfused autologous blood and of transfused allogeneic packed red blood cell units were documented within 48 h after the system change and compared to the measurements obtained from former ECMO-system changes without using any autotransfusion device. We determined the Horrowitz-index, Interleukin 6, 10, TNF-alpha and endothelin-I concentrations and coagulation parameters during the 48 hours after system change to study the compatibility of this procedure. Allogeneic blood transfusion was reduced from 7 to 2 units of packed red cells using the autotransfusion device. Additionally, no hints of any harmful side effects in these patients was observed.
ISSN:0391-3988
1724-6040
DOI:10.1177/039139880002301210