Demonstration of 'cardiac-specific' myosin heavy chain in masticatory muscles of human and rabbit

Human and rabbit masticatory muscles were analyzed immuno- and enzyme-histochemically using antibodies specific to 'cardiac' alpha, slow and fast myosin heavy chain isoforms. In human masseter, temporalis, and lateral pterygoid muscle 'cardiac' alpha myosin heavy chain is found i...

Full description

Saved in:
Bibliographic Details
Published in:The Histochemical journal 1991-04, Vol.23 (4), p.160-170
Main Authors: BREDMAN, J. J, WESSELS, A, WEIJS, W. A, KORFAGE, J. A. M, SOFFERS, C. A. S, MOORMAN, A. F. M
Format: Article
Language:English
Subjects:
Adult
Animals
Antibodies, Monoclonal - immunology
Biological and medical sciences
Blotting, Western
Calcium-Transporting ATPases - analysis
Fundamental and applied biological sciences. Psychology
Heart - physiology
Humans
Immunohistochemistry
Masticatory Muscles - chemistry
Masticatory Muscles - ultrastructure
Myosins - analysis
Neck Muscles - chemistry
Neck Muscles - ultrastructure
Rabbits
Rats
Striated muscle. Tendons
Vertebrates: osteoarticular system, musculoskeletal system
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Human and rabbit masticatory muscles were analyzed immuno- and enzyme-histochemically using antibodies specific to 'cardiac' alpha, slow and fast myosin heavy chain isoforms. In human masseter, temporalis, and lateral pterygoid muscle 'cardiac' alpha myosin heavy chain is found in fibres that contain either fast, or fast and slow myosin heavy chain. In rabbit masseter, temporalis and digastric muscles, fibres are present that express 'cardiac' alpha myosin heavy chain either exclusively, or concomitantly with slow myosin heavy chain or fast myosin heavy chain. Our results demonstrate a much broader distribution of 'cardiac' alpha myosin heavy chain than hitherto recognized and these might explain in part the specific characteristics of masticatory muscles. The 'cardiac' alpha myosin heavy chain is only found in skeletal muscles originating from the cranial part of the embryo (including the heart muscle), suggesting that its expression might be determined by the developmental history of these muscles.
ISSN:0018-2214
1573-6865
DOI:10.1007/bf01046587