Carcinoma arising in an odontogenic keratocyst with orbital invasion

A 54-year-old black female presented with proptosis and reduced visual acuity of the left eye. Computerized tomography (CT) revealed tumor involvement of the left cavernous sinus and posterior orbit. The patient had a nineteen year history of a left-sided jaw tumor which recurred despite surgical an...

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Bibliographic Details
Published in:Documenta ophthalmologica 1991-01, Vol.77 (1), p.73-79
Main Authors: HENNIS, H. L, STEWART, W. C, NEVILLE, B, O'CONNOR, K. F, APPLE, D. J
Format: Article
Language:English
Subjects:
Biological and medical sciences
Carcinoma, Squamous Cell - pathology
Cavernous Sinus - pathology
Cell Transformation, Neoplastic
Female
Humans
Magnetic Resonance Imaging
Medical sciences
Middle Aged
Neoplasm Invasiveness - pathology
Neoplasm Recurrence, Local
Odontogenic Tumors - pathology
Ophthalmology
Orbital Neoplasms - pathology
Tomography, X-Ray Computed
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Description
Summary:A 54-year-old black female presented with proptosis and reduced visual acuity of the left eye. Computerized tomography (CT) revealed tumor involvement of the left cavernous sinus and posterior orbit. The patient had a nineteen year history of a left-sided jaw tumor which recurred despite surgical and radiation therapy. Biopsy demonstrated a parakeratinized odontogenic keratocyst with areas of transformation into an invasive squamous cell carcinoma. Although a parakeratinized odontogenic keratocyst may be locally invasive, to our knowledge, no case of a parakeratinized odontogenic keratocyst involving the orbit or cavernous sinus previously has been reported.
ISSN:0012-4486
1573-2622
DOI:10.1007/BF00154879