Phosphate glass cement bone graft

The objective of this study was to prepare cement-forming substances from phosphate glasses for use as a bone graft. The glass-forming system of CaO-SrO-Na 2O-P 2O 5 was explored and ten phosphate glasses were prepared of varying compositions. Cements were made by reducing the glass to powders and r...

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Bibliographic Details
Published in:Biomaterials 1991-08, Vol.12 (6), p.561-564
Main Authors: Chen, W.S., Monroe, E.A.
Format: Article
Language:English
Subjects:
Biocompatible Materials
Biological and medical sciences
bone graft
Bone Transplantation
calcium phosphate
Ceramic cement
Glass Ionomer Cements - chemical synthesis
Glass Ionomer Cements - chemistry
Hydrogen-Ion Concentration
Materials Testing
Medical sciences
Microscopy, Electron, Scanning
Orthopedic surgery
phosphate glass
Solubility
Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases
X-Ray Diffraction
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Summary:The objective of this study was to prepare cement-forming substances from phosphate glasses for use as a bone graft. The glass-forming system of CaO-SrO-Na 2O-P 2O 5 was explored and ten phosphate glasses were prepared of varying compositions. Cements were made by reducing the glass to powders and reacting them with a water solution of calcium hydroxide or phosphoric acid. The cements were evaluated by X-ray diffraction, electron microscopy, density and porosity measurements, pH change during reaction and solubility in water. Because of the water solubilities of these cement materials, they may be useful as bone grafts containing drugs such as antibiotics which would be slowly released as the graft material degrades.
ISSN:0142-9612
1878-5905
DOI:10.1016/0142-9612(91)90051-B