Reproducibility of asystole during head-up tilt testing in patients with neurally mediated syncope

Tilt induced prolonged asystole has been considered to identify a distinct subgroup of patients with neurally mediated syncope and management including permanent pacemaker implantation has been suggested. To evaluate the reproducibility of asystolic response during head-up tilt testing (HUT), 33 pat...

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Bibliographic Details
Published in:Europace (London, England) England), 2002-10, Vol.4 (4), p.365-367
Main Authors: Foglia-Manzillo, G, Romanò, M, Corrado, G, Tagliagambe, L M, Tadeo, G, Spata, M, Spinelli, A, Grieco, A, Santarone, M
Format: Article
Language:English
Subjects:
Adolescent
Adult
Aged
Child
Female
Heart Arrest
Humans
Male
Middle Aged
Prospective Studies
Reproducibility of Results
Syncope, Vasovagal - diagnosis
Tilt-Table Test
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Summary:Tilt induced prolonged asystole has been considered to identify a distinct subgroup of patients with neurally mediated syncope and management including permanent pacemaker implantation has been suggested. To evaluate the reproducibility of asystolic response during head-up tilt testing (HUT), 33 patients with neurally mediated syncope and asystolic response (> or = 3 seconds) during HUT prospectively underwent two consecutive tests 13 +/- 15 days apart. On repeat tilt testing asystole was reproduced in 12 patients (36%), while 8 patients still had a positive HUT, but without asystole. Remarkably, 13 patients (40%) had a negative repeat HUT. Among 12 patients with asystole on both HUTs there was no significant difference in duration of asystole (14 371 +/- 11 430 ms vs 13 707 +/- 10 470 ms, P = ns) and time to syncope (36 +/- 20 min vs 37 +/- 20 min, P = ns) during initial and repeat HUTs. In conclusion, asystole during tilt testing does not seem to be a reproducible response.
ISSN:1099-5129
DOI:10.1053/eupc.2002.0260