No Evidence of HIV-2 Infection in Subjects at Risk for AIDS Living in North-East Italy

Sera samples from 1134 individuals (824 HIV-1 seropositive and 310 HIV-1 seronegative), collected from January 1988 to April 1990, were tested for HIV-2 antibodies by whole virus assays and synthetic peptide-based assays to determine the prevalence of HIV-2 infection in populations at risk for AIDS...

Full description

Saved in:
Bibliographic Details
Published in:European journal of epidemiology 1991-11, Vol.7 (6), p.682-685
Main Authors: Del Mistro, A., De Rossi, A., Francavilla, E., Sartori, M. T., Chieco-Bianchi, L.
Format: Article
Language:English
Subjects:
Acquired Immunodeficiency Syndrome - epidemiology
Acquired Immunodeficiency Syndrome - immunology
AIDS
AIDS/HIV
Antibodies
Enzyme linked immunosorbent assay
HIV
HIV 1
HIV 2
HIV Antibodies - analysis
HIV Infections - epidemiology
HIV Infections - immunology
HIV Seropositivity - epidemiology
HIV Seropositivity - immunology
HIV-1 - immunology
Homosexuality
human immunodeficiency virus 2
Humans
Infections
Italy - epidemiology
Prevalence
Reactivity
Risk Factors
Seroepidemiologic Studies
Viruses
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Sera samples from 1134 individuals (824 HIV-1 seropositive and 310 HIV-1 seronegative), collected from January 1988 to April 1990, were tested for HIV-2 antibodies by whole virus assays and synthetic peptide-based assays to determine the prevalence of HIV-2 infection in populations at risk for AIDS in North-East Italy (Veneto Region). Partial reactivities on HIV-2 Western Blot were a common finding in HIV-1 seropositive samples. None of the sera fulfilled the criteria for HIV-2 seropositivity, since only low-level reactivity was observed with an HIV-2 competitive ELISA test, and no reactivity occurred with an HIV-2 specific peptide. Therefore, there is no evidence of HIV-2 infection in this geographical area, to date.
ISSN:0393-2990
1573-7284
DOI:10.1007/BF00218682