Loading…
Detection of a Novel Pattern of Connexin 43 Immunoreactivity Responsive to Dehydration in Rat Hypothalamic Magnocellular Nuclei
Immunocytochemical expression of Connexin 43 (Cx 43) in the rat Supraoptic Nucleus was analyzed following dehydration, using sequence-specific anti-Cx 43 antibodies (designated 13-8300, 71-0700, and sc-9059) that exhibit differential recognition of Cx 43. Punctate and longitudinally arranged immunos...
Saved in:
| Published in: | Experimental neurology 2002-09, Vol.177 (1), p.321-325 |
|---|---|
| Main Authors: | , |
| Format: | Article |
| Language: | English |
| Subjects: | |
| Citations: | Items that this one cites Items that cite this one |
| Online Access: | Get full text |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| cited_by | cdi_FETCH-LOGICAL-c370t-9575ad0250e6ef6999f3be6b189961cdf7f5133fabab3e18d190ef2099bba6cc3 |
|---|---|
| cites | cdi_FETCH-LOGICAL-c370t-9575ad0250e6ef6999f3be6b189961cdf7f5133fabab3e18d190ef2099bba6cc3 |
| container_end_page | 325 |
| container_issue | 1 |
| container_start_page | 321 |
| container_title | Experimental neurology |
| container_volume | 177 |
| creator | Eisner, Ines Colombo, Jorge A. |
| description | Immunocytochemical expression of Connexin 43 (Cx 43) in the rat Supraoptic Nucleus was analyzed following dehydration, using sequence-specific anti-Cx 43 antibodies (designated 13-8300, 71-0700, and sc-9059) that exhibit differential recognition of Cx 43. Punctate and longitudinally arranged immunostaining patterns of Cx 43 labeling, as evidenced by antibody sc-9059, was detected overlaying the nucleus of magnocellular neuroendocrine cells. This novel form of longitudinally arranged Cx 43 immunoreactivity was modified by dehydration and halothane exposure, but not lactation. |
| doi_str_mv | 10.1006/exnr.2002.7953 |
| format | article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_72675760</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><els_id>S0014488602979537</els_id><sourcerecordid>72675760</sourcerecordid><originalsourceid>FETCH-LOGICAL-c370t-9575ad0250e6ef6999f3be6b189961cdf7f5133fabab3e18d190ef2099bba6cc3</originalsourceid><addsrcrecordid>eNp1kT1vFDEQhi0EIpdAS4ncQLfH2N4vl-gSSKQQUAS15fWOidGufdjeU67ir7N7d1KqVCONnvfV6BlC3jFYM4D6Ez76uOYAfN3ISrwgKwYSCl4KeElWAKwsyratz8h5Sn8AQJa8eU3OGC-55KJckX-XmNFkFzwNlmp6F3Y40B86Z4yH1SZ4j4_O01LQm3GcfIio58DO5T29x7QNPrkd0hzoJT7s-6gPZXPgXmd6vd-G_KAHPTpDv-nfPhgchmnQkd5NZkD3hryyekj49jQvyK8vVz8318Xt9683m8-3hREN5EJWTaV74BVgjbaWUlrRYd2xVsqamd42tmJCWN3pTiBreyYBLQcpu07XxogL8vHYu43h74Qpq9Gl5RbtMUxJNbxuqqaGGVwfQRNDShGt2kY36rhXDNSiXC3K1aJcLcrnwPtT89SN2D_hJ8cz8OEE6GT0YKP2xqUnTkhRNweuPXI4e9g5jCoZh95g7-L8ItUH99wN_wHn2Z9g</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>72675760</pqid></control><display><type>article</type><title>Detection of a Novel Pattern of Connexin 43 Immunoreactivity Responsive to Dehydration in Rat Hypothalamic Magnocellular Nuclei</title><source>ScienceDirect Freedom Collection</source><creator>Eisner, Ines ; Colombo, Jorge A.</creator><creatorcontrib>Eisner, Ines ; Colombo, Jorge A.</creatorcontrib><description>Immunocytochemical expression of Connexin 43 (Cx 43) in the rat Supraoptic Nucleus was analyzed following dehydration, using sequence-specific anti-Cx 43 antibodies (designated 13-8300, 71-0700, and sc-9059) that exhibit differential recognition of Cx 43. Punctate and longitudinally arranged immunostaining patterns of Cx 43 labeling, as evidenced by antibody sc-9059, was detected overlaying the nucleus of magnocellular neuroendocrine cells. This novel form of longitudinally arranged Cx 43 immunoreactivity was modified by dehydration and halothane exposure, but not lactation.</description><identifier>ISSN: 0014-4886</identifier><identifier>EISSN: 1090-2430</identifier><identifier>DOI: 10.1006/exnr.2002.7953</identifier><identifier>PMID: 12429234</identifier><identifier>CODEN: EXNEAC</identifier><language>eng</language><publisher>Amsterdam: Elsevier Inc</publisher><subject>Animals ; astroglia ; Biological and medical sciences ; cell coupling ; connexin 43 ; Connexin 43 - analysis ; Connexin 43 - biosynthesis ; Connexin 43 - immunology ; Dehydration - immunology ; Dehydration - metabolism ; Diseases of striated muscles. Neuromuscular diseases ; Female ; gap junctions ; Immunohistochemistry ; Lactation - physiology ; Male ; Medical sciences ; neural plasticity ; Neurology ; Rats ; Rats, Sprague-Dawley ; supraoptic nucleus ; Supraoptic Nucleus - chemistry ; Supraoptic Nucleus - metabolism</subject><ispartof>Experimental neurology, 2002-09, Vol.177 (1), p.321-325</ispartof><rights>2002 Elsevier Science (USA)</rights><rights>2003 INIST-CNRS</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c370t-9575ad0250e6ef6999f3be6b189961cdf7f5133fabab3e18d190ef2099bba6cc3</citedby><cites>FETCH-LOGICAL-c370t-9575ad0250e6ef6999f3be6b189961cdf7f5133fabab3e18d190ef2099bba6cc3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,27924,27925</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=13936734$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/12429234$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Eisner, Ines</creatorcontrib><creatorcontrib>Colombo, Jorge A.</creatorcontrib><title>Detection of a Novel Pattern of Connexin 43 Immunoreactivity Responsive to Dehydration in Rat Hypothalamic Magnocellular Nuclei</title><title>Experimental neurology</title><addtitle>Exp Neurol</addtitle><description>Immunocytochemical expression of Connexin 43 (Cx 43) in the rat Supraoptic Nucleus was analyzed following dehydration, using sequence-specific anti-Cx 43 antibodies (designated 13-8300, 71-0700, and sc-9059) that exhibit differential recognition of Cx 43. Punctate and longitudinally arranged immunostaining patterns of Cx 43 labeling, as evidenced by antibody sc-9059, was detected overlaying the nucleus of magnocellular neuroendocrine cells. This novel form of longitudinally arranged Cx 43 immunoreactivity was modified by dehydration and halothane exposure, but not lactation.</description><subject>Animals</subject><subject>astroglia</subject><subject>Biological and medical sciences</subject><subject>cell coupling</subject><subject>connexin 43</subject><subject>Connexin 43 - analysis</subject><subject>Connexin 43 - biosynthesis</subject><subject>Connexin 43 - immunology</subject><subject>Dehydration - immunology</subject><subject>Dehydration - metabolism</subject><subject>Diseases of striated muscles. Neuromuscular diseases</subject><subject>Female</subject><subject>gap junctions</subject><subject>Immunohistochemistry</subject><subject>Lactation - physiology</subject><subject>Male</subject><subject>Medical sciences</subject><subject>neural plasticity</subject><subject>Neurology</subject><subject>Rats</subject><subject>Rats, Sprague-Dawley</subject><subject>supraoptic nucleus</subject><subject>Supraoptic Nucleus - chemistry</subject><subject>Supraoptic Nucleus - metabolism</subject><issn>0014-4886</issn><issn>1090-2430</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2002</creationdate><recordtype>article</recordtype><recordid>eNp1kT1vFDEQhi0EIpdAS4ncQLfH2N4vl-gSSKQQUAS15fWOidGufdjeU67ir7N7d1KqVCONnvfV6BlC3jFYM4D6Ez76uOYAfN3ISrwgKwYSCl4KeElWAKwsyratz8h5Sn8AQJa8eU3OGC-55KJckX-XmNFkFzwNlmp6F3Y40B86Z4yH1SZ4j4_O01LQm3GcfIio58DO5T29x7QNPrkd0hzoJT7s-6gPZXPgXmd6vd-G_KAHPTpDv-nfPhgchmnQkd5NZkD3hryyekj49jQvyK8vVz8318Xt9683m8-3hREN5EJWTaV74BVgjbaWUlrRYd2xVsqamd42tmJCWN3pTiBreyYBLQcpu07XxogL8vHYu43h74Qpq9Gl5RbtMUxJNbxuqqaGGVwfQRNDShGt2kY36rhXDNSiXC3K1aJcLcrnwPtT89SN2D_hJ8cz8OEE6GT0YKP2xqUnTkhRNweuPXI4e9g5jCoZh95g7-L8ItUH99wN_wHn2Z9g</recordid><startdate>20020901</startdate><enddate>20020901</enddate><creator>Eisner, Ines</creator><creator>Colombo, Jorge A.</creator><general>Elsevier Inc</general><general>Elsevier</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>20020901</creationdate><title>Detection of a Novel Pattern of Connexin 43 Immunoreactivity Responsive to Dehydration in Rat Hypothalamic Magnocellular Nuclei</title><author>Eisner, Ines ; Colombo, Jorge A.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c370t-9575ad0250e6ef6999f3be6b189961cdf7f5133fabab3e18d190ef2099bba6cc3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2002</creationdate><topic>Animals</topic><topic>astroglia</topic><topic>Biological and medical sciences</topic><topic>cell coupling</topic><topic>connexin 43</topic><topic>Connexin 43 - analysis</topic><topic>Connexin 43 - biosynthesis</topic><topic>Connexin 43 - immunology</topic><topic>Dehydration - immunology</topic><topic>Dehydration - metabolism</topic><topic>Diseases of striated muscles. Neuromuscular diseases</topic><topic>Female</topic><topic>gap junctions</topic><topic>Immunohistochemistry</topic><topic>Lactation - physiology</topic><topic>Male</topic><topic>Medical sciences</topic><topic>neural plasticity</topic><topic>Neurology</topic><topic>Rats</topic><topic>Rats, Sprague-Dawley</topic><topic>supraoptic nucleus</topic><topic>Supraoptic Nucleus - chemistry</topic><topic>Supraoptic Nucleus - metabolism</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Eisner, Ines</creatorcontrib><creatorcontrib>Colombo, Jorge A.</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Experimental neurology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Eisner, Ines</au><au>Colombo, Jorge A.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Detection of a Novel Pattern of Connexin 43 Immunoreactivity Responsive to Dehydration in Rat Hypothalamic Magnocellular Nuclei</atitle><jtitle>Experimental neurology</jtitle><addtitle>Exp Neurol</addtitle><date>2002-09-01</date><risdate>2002</risdate><volume>177</volume><issue>1</issue><spage>321</spage><epage>325</epage><pages>321-325</pages><issn>0014-4886</issn><eissn>1090-2430</eissn><coden>EXNEAC</coden><abstract>Immunocytochemical expression of Connexin 43 (Cx 43) in the rat Supraoptic Nucleus was analyzed following dehydration, using sequence-specific anti-Cx 43 antibodies (designated 13-8300, 71-0700, and sc-9059) that exhibit differential recognition of Cx 43. Punctate and longitudinally arranged immunostaining patterns of Cx 43 labeling, as evidenced by antibody sc-9059, was detected overlaying the nucleus of magnocellular neuroendocrine cells. This novel form of longitudinally arranged Cx 43 immunoreactivity was modified by dehydration and halothane exposure, but not lactation.</abstract><cop>Amsterdam</cop><pub>Elsevier Inc</pub><pmid>12429234</pmid><doi>10.1006/exnr.2002.7953</doi><tpages>5</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0014-4886 |
| ispartof | Experimental neurology, 2002-09, Vol.177 (1), p.321-325 |
| issn | 0014-4886 1090-2430 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_72675760 |
| source | ScienceDirect Freedom Collection |
| subjects | Animals astroglia Biological and medical sciences cell coupling connexin 43 Connexin 43 - analysis Connexin 43 - biosynthesis Connexin 43 - immunology Dehydration - immunology Dehydration - metabolism Diseases of striated muscles. Neuromuscular diseases Female gap junctions Immunohistochemistry Lactation - physiology Male Medical sciences neural plasticity Neurology Rats Rats, Sprague-Dawley supraoptic nucleus Supraoptic Nucleus - chemistry Supraoptic Nucleus - metabolism |
| title | Detection of a Novel Pattern of Connexin 43 Immunoreactivity Responsive to Dehydration in Rat Hypothalamic Magnocellular Nuclei |
| url | http://sfxeu10.hosted.exlibrisgroup.com/loughborough?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-02T16%3A38%3A46IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Detection%20of%20a%20Novel%20Pattern%20of%20Connexin%2043%20Immunoreactivity%20Responsive%20to%20Dehydration%20in%20Rat%20Hypothalamic%20Magnocellular%20Nuclei&rft.jtitle=Experimental%20neurology&rft.au=Eisner,%20Ines&rft.date=2002-09-01&rft.volume=177&rft.issue=1&rft.spage=321&rft.epage=325&rft.pages=321-325&rft.issn=0014-4886&rft.eissn=1090-2430&rft.coden=EXNEAC&rft_id=info:doi/10.1006/exnr.2002.7953&rft_dat=%3Cproquest_cross%3E72675760%3C/proquest_cross%3E%3Cgrp_id%3Ecdi_FETCH-LOGICAL-c370t-9575ad0250e6ef6999f3be6b189961cdf7f5133fabab3e18d190ef2099bba6cc3%3C/grp_id%3E%3Coa%3E%3C/oa%3E%3Curl%3E%3C/url%3E&rft_id=info:oai/&rft_pqid=72675760&rft_id=info:pmid/12429234&rfr_iscdi=true |