A Modified Hepatitis B Virus Core Particle Containing Multiple Epitopes of the Plasmodium falciparum Circumsporozoite Protein Provides a Highly Immunogenic Malaria Vaccine in Preclinical Analyses in Rodent and Primate Hosts

• Published in: Infection and Immunity 2002-12, Vol.70 (12), p.6860-6870
• Main Authors: Birkett, A., Lyons, K., Schmidt, A., Boyd, D., Oliveira, G. A., Siddique, A., Nussenzweig, R., Calvo-Calle, J. M., Nardin, E.
• Format: Article
• Language: English
• Subjects: Amino Acid Sequence; Animals; Antibodies, Protozoan - blood; Base Sequence; Biological and medical sciences; Cell Line; Epitopes, B-Lymphocyte - chemistry; Epitopes, T-Lymphocyte - chemistry; Fundamental and applied biological sciences. Psychology; Fungal and Parasitic Infections; Hepatitis B Core Antigens - genetics; Hepatitis B Core Antigens - immunology; Humans; Immunization; Macaca fascicularis; Malaria - prevention & control; Malaria Vaccines - immunology; Mice; Mice, Inbred BALB C; Molecular Sequence Data; Plasmodium falciparum - immunology; Protozoa; Protozoan Proteins - chemistry; Protozoan Proteins - genetics; Protozoan Proteins - immunology; T-Lymphocytes - immunology; Vaccines, antisera, therapeutical immunoglobulins and monoclonal antibodies
• ISSN: 0019-9567; 1098-5522
• DOI: 10.1128/IAI.70.12.6860-6870.2002

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