Distribution of bone mineral density at the proximal tibia in knee osteoarthritis

• Published in: Calcified tissue international 2002-10, Vol.71 (4), p.315-322
• Main Authors: Hulet, C, Sabatier, J P, Souquet, D, Locker, B, Marcelli, C, Vielpeau, C
• Format: Article
• Language: English
• Subjects: Absorptiometry, Photon; Aged; Bone Density; Female; Femur Neck - diagnostic imaging; Femur Neck - pathology; Humans; Male; Osteoarthritis, Knee - complications; Osteoarthritis, Knee - pathology; Osteoarthritis, Knee - physiopathology; Osteoporosis, Postmenopausal - complications; Osteoporosis, Postmenopausal - pathology; Osteoporosis, Postmenopausal - physiopathology; Tibia - pathology
• ISSN: 0171-967X; 1432-0827
• DOI: 10.1007/s00223-001-2112-9

One hundred and thirteen knees with osteoarthritis (OA) were studied to assess the distribution of bone mineral density (BMD) in the proximal tibia and the potential relation between osteoarthritis and osteoporosis in evaluating hip BMD. All patients had severe knee pain and were diagnosed with Kellgren and Lawrence grade IV osteoarthritis. According to the magnitude of the axial deformity, four categories were created: varus>10 degrees ( 28.3%), varus 4-10 degrees (38.9%), aligned 180 +/- 3 degrees (13.3%), and valgus>4 degrees (19.5%). For each category, the medial and lateral proximal tibial density were assessed. BMD was measured at the femoral neck and at 14 regions of interest (ROI) in the proximal part of the tibia using dual X-ray absorptiometry. Based on the femoral neck BMD, patients were classified according to the World Health Organization (WHO) definition of osteoporosis. The mean knee BMD was positively correlated with the hip BMD value (knee BMD m = 0.38 + 0.73 x hip BMD, r = 0.60, P