Effect of acute changes in aortic pressure on the coronary reserve

Study objective — The aim was to evaluate the effect of acute changes in aortic pressure on the coronary reserve and hyperaemic response. Design — Aortic pressure changes were induced either by intra-aortic balloon pumping or by the production of acute aortic regurgitation. A transient 20 s occlusio...

Full description

Saved in:
Bibliographic Details
Published in:Cardiovascular research 1991-12, Vol.25 (12), p.995-1001
Main Authors: Antonatos, P G, Foussas, S G, Nanas, S N, Karamoussalis, D G, Theocharis, A G, Anthopoulos, L P, Moulopoulos, S D
Format: Article
Language:English
Subjects:
Animals
Aorta, Thoracic - physiopathology
aortic pressure
aortic regurgitation
Aortic Valve Insufficiency - physiopathology
Arterial Occlusive Diseases - physiopathology
balloon pumping
Biological and medical sciences
Blood Pressure - physiology
Cardiology. Vascular system
Coronary Circulation - physiology
coronary reserve
Dilatation, Pathologic
Disease Models, Animal
Dogs
Endocardial and cardiac valvular diseases
Heart
Hyperemia - physiopathology
intra-aortic
Intra-Aortic Balloon Pumping
Medical sciences
Regional Blood Flow - physiology
Citations: Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Study objective — The aim was to evaluate the effect of acute changes in aortic pressure on the coronary reserve and hyperaemic response. Design — Aortic pressure changes were induced either by intra-aortic balloon pumping or by the production of acute aortic regurgitation. A transient 20 s occlusion of the left anterior descending coronary artery was used as the hyperaemic stimulus Experimental subjects — The experiments were performed on 19 open chest anaesthetised dogs, weight 13-32 kg. Measurements and main results — During intra-aortic balloon pumping the mean diastolic aortic pressure increased by 24.7(SEM 2.9) mm Hg (p
ISSN:0008-6363
1755-3245
DOI:10.1093/cvr/25.12.995