Investigation on the wound healing activity of oleo-resin from Copaifera langsdorffi in rats

The wound healing activity of oleo‐resin from Copaifera langsdorffii Desf. (Leguminaceae) bark was evaluated in rats on experimental wounds. The oleo‐resin was tested by monitoring wound contraction in excised wounds and by measuring tensile strength in healing incision wounds. The topical applicati...

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Bibliographic Details
Published in:Phytotherapy research 2002-12, Vol.16 (8), p.737-739
Main Authors: Paiva, L. A. F., de Alencar Cunha, K. M., Santos, F. A., Gramosa, N. V., Silveira, E. R., Rao, V. S. N.
Format: Article
Language:English
Subjects:
Administration, Cutaneous
Animals
Balsams - administration & dosage
Balsams - pharmacology
Balsams - therapeutic use
Biological and medical sciences
Copaifera langsdorffii
experimental wounds
Fabaceae
General pharmacology
Male
Medical sciences
oleo-resin
Pharmacognosy. Homeopathy. Health food
Pharmacology. Drug treatments
Phytotherapy
Rats
Rats, Wistar
Tensile Strength - drug effects
wound healing
Wound Healing - drug effects
Wound Healing - physiology
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Summary:The wound healing activity of oleo‐resin from Copaifera langsdorffii Desf. (Leguminaceae) bark was evaluated in rats on experimental wounds. The oleo‐resin was tested by monitoring wound contraction in excised wounds and by measuring tensile strength in healing incision wounds. The topical application of oleo‐resin at a concentration of 4% accelerated wound contraction in open wounds. The mean values of wound contraction in oleo‐resin treated rats on day 9 was 84.05% ± 2.37% as against 51.29% ± 9.54% seen in controls and the difference was statistically significant (p 
ISSN:0951-418X
1099-1573
DOI:10.1002/ptr.1049