HER-2/neu Oncogene Sequence Revisited

In the course of developing DNA vaccines for transgenic models of breast cancer, we cloned the second cystein-- rich domain (CRD-2) of the extracellular domain of the rat neu gene (X03362; nucleotides 1456-1987) by polymerase chain reaction (PCR) amplification of PSV2 neuT plasmid (3) (provided by P...

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Bibliographic Details
Published in:JNCI : Journal of the National Cancer Institute 2002-12, Vol.94 (23), p.1808-1809
Main Authors: Venanzi, Franco M., Soverchia, Laura, Felicetti, Paola, Mennecozzi, Milena, Concetti, Antonio
Format: Article
Language:English
Subjects:
Animals
Breast cancer
Cytosine - analysis
Deoxyribonucleic acid
DNA
DNA, Complementary - analysis
DNA, Neoplasm - analysis
Gene Deletion
Genes
Humans
Mice
Mice, Transgenic
Molecular Sequence Data
Mutation
Polymerase Chain Reaction
Rats
Rats, Sprague-Dawley
Receptor, ErbB-2 - genetics
Sequence Analysis, DNA
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Description
Summary:In the course of developing DNA vaccines for transgenic models of breast cancer, we cloned the second cystein-- rich domain (CRD-2) of the extracellular domain of the rat neu gene (X03362; nucleotides 1456-1987) by polymerase chain reaction (PCR) amplification of PSV2 neuT plasmid (3) (provided by Professor N. Ranzani, University of Pavia, Italy).
ISSN:0027-8874
1460-2105
1460-2105
DOI:10.1093/jnci/94.23.1808