Quantitative CT for the evaluation of bone healing

Quantitative computed tomography (QCT) was used to quantitate the structural strength and local material properties of healing tibial osteotomies in 32 dogs. Dogs were divided into four equal groups, euthanatized at either 2, 4, 8, or 12 weeks and imaged with QCT. Invasive techniques were used to de...

Full description

Saved in:
Bibliographic Details
Published in:Calcified tissue international 1991-12, Vol.49 (6), p.427-432
Main Authors: MARKEL, M. D, MORIN, R. L, WIKENHEISER, M. A, LEWALLEN, D. G, CHAO, E. Y. S
Format: Article
Language:English
Subjects:
Animals
Biological and medical sciences
Bone Density
Calcification, Physiologic
Calcium - analysis
Diseases of the osteoarticular system
Dogs
Female
Male
Medical sciences
Miscellaneous. Osteoarticular involvement in other diseases
Osteotomy
Space life sciences
Tibial Fractures - physiopathology
Tomography, X-Ray Computed
Wound Healing
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Quantitative computed tomography (QCT) was used to quantitate the structural strength and local material properties of healing tibial osteotomies in 32 dogs. Dogs were divided into four equal groups, euthanatized at either 2, 4, 8, or 12 weeks and imaged with QCT. Invasive techniques were used to determine (1) the torsional properties of the bone; (2) the local stiffness properties and calcium content within the bone; and (3) histologically determined new bone formation and porosity. QCT was strongly associated with the maximum torque (R2 = 0.44) and torsional stiffness (R2 = 0.69) of the healing bone. QCT had strong correlations with the local stiffness (R2 = 0.64), calcium content (R2 = 0.61), new bone (R2 = 0.84), and porosity (R2 = 0.84) of healing tissues.
ISSN:0171-967X
1432-0827
DOI:10.1007/BF02555855