Medical Grade Calcium Sulfate Hemihydrate Versus Expanded Polytetrafluoroethylene in the Treatment of Mandibular Class II Furcations

Background: Guided tissue regeneration (GTR) techniques have been reported to enhance bone regeneration of molar furcation defects. The current trends in therapy encourage the use of a bioabsorbable barrier. The efficacy of the bioabsorbable barrier needs to be equal to, if not better than, the non‐...

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Bibliographic Details
Published in:Journal of periodontology (1970) 2002-11, Vol.73 (11), p.1352-1359
Main Authors: Couri, Christopher J., Maze, Glenn I., Hinkson, David W., Collins, Byran H., Dawson, Deborah V.
Format: Article
Language:English
Subjects:
Absorbable Implants
Adult
Aged
Bone Regeneration
Bone Transplantation - methods
Calcium Sulfate
comparison studies
Dentistry
Female
Furcation Defects - surgery
Furcation/therapy
guided bone regeneration
Guided Tissue Regeneration, Periodontal - methods
Humans
Male
Mandible
Membranes, Artificial
membranes, bioabsorbable
membranes/barrier
Middle Aged
Molar
Periodontitis - surgery
Polytetrafluoroethylene
polytetrafluoroethylene/therapeutic use
Statistics, Nonparametric
Treatment Outcome
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Summary:Background: Guided tissue regeneration (GTR) techniques have been reported to enhance bone regeneration of molar furcation defects. The current trends in therapy encourage the use of a bioabsorbable barrier. The efficacy of the bioabsorbable barrier needs to be equal to, if not better than, the non‐absorbable barrier. Methods: This clinical study compared the bone regeneration capacity of a commonly used GTR procedure (demineralized freezedried bone allograft [DFDBA] and an expanded polytetrafluoroethylene [ePTFE] membrane) to DFDBA and an exclusion barrier of medical grade calcium sulfate hemihydrate [MGCSH]). Thirteen pairs of mandibular molar Class II furcation defects were evaluated in 13 patients. Clinical measurements of keratinized gingival width, probing depth, and recession were recorded prior to treatment. Following flap elevation and furcation defect debridement, an occlusal reference stent and periodontal probes were used to measure vertical, horizontal, and intrabony defect dimensions to the nearest millimeter. Paired defects were randomly assigned to receive either DFDBA/ePTFE or DFDBA/MGCSH. At 6 months, study sites were surgically re‐entered and the treated furcations were debrided to a firm bone surface. Intraoperative measurements were repeated. Clinical measurements were repeated at 12 months. Results: The MGCSH‐treated furcations demonstrated mean probing depth reduction between baseline and 6 months (1.00 ± 0.82 mm, P
ISSN:0022-3492
1943-3670
DOI:10.1902/jop.2002.73.11.1352