Novel Nucleophilic Trifluoromethylation of Vicinal Diol Cyclic Sulfates

A novel method for highly regioselective and stereospecific nucleophilic trifluoromethylation of vicinal diol cyclic sulfates, using the reagent derived from reduction of trifluoromethyl iodide by tetrakis(dimethylamino)ethylene (TDAE), is presented.

Saved in:
Bibliographic Details
Published in:Organic letters 2002-12, Vol.4 (26), p.4671-4672
Main Authors: Takechi, Naoto, Ait-Mohand, Samia, Medebielle, Maurice, Dolbier, William R
Format: Article
Language:English
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:A novel method for highly regioselective and stereospecific nucleophilic trifluoromethylation of vicinal diol cyclic sulfates, using the reagent derived from reduction of trifluoromethyl iodide by tetrakis(dimethylamino)ethylene (TDAE), is presented.
ISSN:1523-7060
1523-7052
DOI:10.1021/ol0270374